ArticleGlobal spine journal2022
What Are the Risk Factors for Adjacent Vertebral Fracture After Vertebral Augmentation? A Meta-Analysis of Published Studies.
Article in Global spine journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Does prophylactic vertebral augmentation reduce the refracture rate in osteoporotic vertebral fracture patients: a meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Pooled it
- Diagnostic value of an S1-normalized CT hounsfield unit ratio for identifying acute fractures in complex thoracolumbar osteoporotic deformities.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Prediction of refracture risk after osteoporotic vertebral compression fracture surgery using the vertebral bone quality index from multi-sequence MRI.Scientific reports · 2026Article
- Intrabody Cage Augmentation in Kümmell Disease and Osteoporotic Burst Fractures: Technical Insights and Narrative Review of Current Evidence.Journal of clinical medicine · 2026Review
- Development and validation of a prediction model for vertebral recompression and adjacent vertebral fracture after kyphoplasty in geriatric patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Development of risk scoring system for adjacent vertebral fractures after percutaneous vertebroplasty.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Comparison of Surgical Outcomes Between Vertebral Body Stenting (VBS) and Balloon Kyphoplasty (BKP)-Multicenter Cohort Study.Journal of clinical medicine · 2026Article
- Risk factors for subsequent vertebral fracture after percutaneous vertebroplasty in patients with osteoporotic vertebral compression fractures in Northern China.Frontiers in surgery · 2026Article
- CT- and MRI-based endplate osteoporosis status assessment for predicting adjacent vertebral fractures after thoracolumbar percutaneous kyphoplasty: a matched comparison study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Association of CT HU Values with Adjacent Vertebral Fractures After Balloon Kyphoplasty.Medicina (Kaunas, Lithuania) · 2025Article
- Safety, Efficacy, and Adjacent-level Fracture Risk Following Vertebral Augmentation and Radiofrequency Ablation for the Treatment of Spine Metastases in Patients with Cancer.Radiology. Imaging cancer · 2025Article
- Article
- Poor bony density can independently trigger higher incidence of adjacent vertebral fracture after percutaneous vertebralplasty: a mono-center retrospective study.Langenbeck's archives of surgery · 2025Article
- Efficiency and Safety of Repeated Vertebroplasty for Adjacent Segment Fractures.Journal of clinical medicine · 2024Article
- Early Balloon Kyphoplasty Treatment for Osteoporotic Vertebral Fracture Reduces Adjacent Vertebral Fractures.Medicina (Kaunas, Lithuania) · 2024Article
- Analysis of adjacent vertebral fracture after percutaneous vertebroplasty: do radiological or surgical features matter?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Development of a nomogram model for prediction of new adjacent vertebral compression fractures after vertebroplasty.BMC surgery · 2023Article
- [Cement augmentation in spinal surgery].Unfallchirurgie (Heidelberg, Germany) · 2022Review
- Does segmental artery occlusion cause intravertebral cleft following osteoporotic vertebral fracture: a prospective magnetic resonance angiography study.BMC musculoskeletal disorders · 2022Article
- Intervertebral bridging ossification after kyphoplasty in a Parkinson's patient with Kummell's disease: A case report.World journal of clinical cases · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designMeta-analysis.
objectivesTo provide up-to-date evidence-based outcomes for the incidence and risk factors of adjacent vertebral fracture (AVF) after the vertebral augmentation.
methodsThe MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials were searched for studies assessing the risk factors of adjacent vertebral fracture after vertebral augmentation until June 2020. The AVF incidence and factors potentially affecting AVF were extracted and pooled.
resultsA total of 16 studies, encompassing 2549 patients were included in the meta-analysis. The pooled incidence of AVF was 14% after vertebral augmentation. Female, lower T-score, thoracolumbar junction fracture, intravertebral cleft, more injected cement volume, intradiscal cement leakage significantly increased the risk of AVF. Age, body mass index, steroid medication, Cobb angle change, postoperative Cobb angle showed no significant association with AVF.
conclusionsIdentifying the risk factors of AVF can facilitate prevention strategy to avoid the AVF. Female, T-score, thoracolumbar junction fracture, intravertebral cleft, more cement volume, and intradiscal cement leakage increased the risk of AVF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.