Evidence map›Paper›PMID 33271919›Full record

ArticleCells2020

Spontaneous Depolarization-Induced Action Potentials of ON-Starburst Amacrine Cells during Cholinergic and Glutamatergic Retinal Waves.

Rong-Shan Yan, Xiong-Li Yang, Yong-Mei Zhong, Dao-Qi Zhang

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Rong-Shan YanInstitutes of Brain Science, Fudan University, Shanghai 200032, China.ORCID 0000-0003-1505-1321
Xiong-Li YangInstitutes of Brain Science, Fudan University, Shanghai 200032, China.
Yong-Mei ZhongInstitutes of Brain Science, Fudan University, Shanghai 200032, China.
Dao-Qi ZhangEye Research Institute, Oakland University, Rochester, MI 48309-4479, USA.
Fudan University · CNOakland University · US

Funding

Functional organization of the retinal dopaminergic networkR01EY022640 · NEI · OAKLAND UNIVERSITY · PI ZHANG, DAO-QI · 2014 to 2018
$1.8M
NEI NIH HHS R01 EY022640
6 · The paper itself

Abstract

Correlated spontaneous activity in the developing retina (termed "retinal waves") plays an instructive role in refining neural circuits of the visual system. Depolarizing (ON) and hyperpolarizing (OFF) starburst amacrine cells (SACs) initiate and propagate cholinergic retinal waves. Where cholinergic retinal waves stop, SACs are thought to be driven by glutamatergic retinal waves initiated by ON-bipolar cells. However, the properties and function of cholinergic and glutamatergic waves in ON- and OFF-SACs still remain poorly understood. In the present work, we performed whole-cell patch-clamp recordings and Ca

Indexed as

AcetylcholineAction PotentialsAmacrine CellsAnimalsAnimals, NewbornCalciumCholinergic AgentsFemaleGlutamatesMaleMiceRetinaAcetylcholineCalciumCholinergic AgentsGlutamatesacetylcholineaction potentialglutamateretinal wavestarburst amacrine cell

Identifiers

PMID33271919
PMCPMC7759856
OpenAlexW3110427650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.