Evidence map›Paper›PMID 33271843›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Social and Contextual Influences on Antibiotic Prescribing and Antimicrobial Stewardship: A Qualitative Study with Clinical Commissioning Group and General Practice Professionals.

Aleksandra J Borek, Sibyl Anthierens, Rosalie Allison, Cliodna A M Mcnulty, Philip E Anyanwu, Ceire Costelloe, Ann Sarah Walker, Christopher C Butler, Sarah Tonkin-Crine, On Behalf Of The Step-Up Study Team

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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  5. GP workforce sustainability to maximise effective and equitable patient care: a realist review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Aleksandra J BorekNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK.ORCID 0000-0001-6029-5291
Sibyl AnthierensDepartment of Family Medicine and Population Health, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0003-4762-1907
Rosalie AllisonPrimary Care and Interventions Unit, Public Health England, Gloucester GL1 1DQ, UK.ORCID 0000-0003-1266-2549
Cliodna A M McnultyPrimary Care and Interventions Unit, Public Health England, Gloucester GL1 1DQ, UK.ORCID 0000-0003-4969-5360
Philip E AnyanwuDepartment of Primary Care and Public Health, Imperial College London, London W6 8RP, UK.
Ceire CostelloeDepartment of Primary Care and Public Health, Imperial College London, London W6 8RP, UK.
Ann Sarah WalkerNational Institute for Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Oxford OX3 9DU, UK.
Christopher C ButlerNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK.ORCID 0000-0002-0102-3453
Sarah Tonkin-CrineNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK.ORCID 0000-0003-4470-1151
On Behalf Of The Step-Up Study Team
National Institute for Health Research · GBImperial College London · GBPublic Health England · GBUniversity of Antwerp · BEUniversity of Oxford · GB

Funding

Department of Health CDF-2016-09-015Economic and Social Research Council (ESRC) through the Antimicrobial Resistance Cross Council Initiative ES/P008232/1National Institute for Health Research (NIHR) Health Protection Research Unit (HPRU) in Healthcare Associated Infections and Antimicrobial Resistance at the University of Oxford in partnership with Public Health England HPRU-2012-10041
6 · The paper itself

Abstract

Antibiotic prescribing in England varies considerably between Clinical Commissioning Groups (CCGs) and general practices. We aimed to assess social and contextual factors affecting antibiotic prescribing and engagement with antimicrobial stewardship (AMS) initiatives. Semi-structured telephone interviews were conducted with 22 CCG professionals and 19 general practice professionals. Interviews were audio-recorded, transcribed, and analyzed thematically. Social/contextual influences were grouped into the following four categories: (1) Immediate context, i.e., patients' social characteristics (e.g., deprivation and culture), clinical factors, and practice and clinician characteristics (e.g., "struggling" with staff shortage/turnover) were linked to higher prescribing. (2) Wider context, i.e., pressures on the healthcare system, limited resources, and competing priorities were seen to reduce engagement with AMS. (3) Collaborative and whole system approaches, i.e., communication, multidisciplinary networks, leadership, and teamwork facilitated prioritizing AMS, learning, and consistency. (4) Relativity of appropriate prescribing, i.e., "high" or "appropriate" prescribing was perceived as relative, depending on comparators, and disregarding different contexts, but social norms around antibiotic use among professionals and patients seemed to be changing. Further optimization of antibiotic prescribing would benefit from addressing social/contextual factors and addressing wider health inequalities, not only targeting individual clinicians. Tailoring and adapting to local contexts and constraints, ensuring adequate time and resources for AMS, and collaborative, whole system approaches to promote consistency may help promote AMS.

Indexed as

antibiotic prescribingantimicrobial stewardshipprimary carequalitative

Identifiers

PMID33271843
PMCPMC7759918
OpenAlexW3109564454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.