ArticleJournal of functional biomaterials2020
Hardness, an Important Indicator of Bone Quality, and the Role of Collagen in Bone Hardness.
Article in Journal of functional biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
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- Objective selection of bone mimetic materials using impact microindentation.Journal of orthopaedics · 2026Article
- Analysis of Biomechanical Characteristics of Bone Tissues Using a Bayesian Neural Network: A Narrative Review.Journal of functional biomaterials · 2025Review
- Hardness Changes Due to the Morphological Evolution of Microstructural Phases in an As-Solidified Zn-Fe Alloy.Materials (Basel, Switzerland) · 2025Article
- Bone-protective effects of deer-hide gelatin in cyclophosphamide-induced osteoporosis rats.Frontiers in pharmacology · 2025Article
- A 0.2 T-0.4 T Static Magnetic Field Improves the Bone Quality of Mice Subjected to Hindlimb Unloading and Reloading Through the Dual Regulation of BMSCs via Iron Metabolism.International journal of molecular sciences · 2024Article
- Microhardness Measurements on Tooth and Alveolar Bone in Rodent Oral Disease Models.Journal of visualized experiments : JoVE · 2024Article
- A Novel Viscoelastic Deformation Mechanism Uncovered during Vickers Hardness Study of Bone.Journal of functional biomaterials · 2024Article
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- A comparative study on the effects of biodegradable high-purity magnesium screw and polymer screw for fixation in epiphyseal trabecular bone.Regenerative biomaterials · 2024Article
- Aerogel-Based Materials in Bone and Cartilage Tissue Engineering-A Review with Future Implications.Gels (Basel, Switzerland) · 2023Review
- Astaxanthin as a Potent Antioxidant for Promoting Bone Health: An Up-to-Date Review.Antioxidants (Basel, Switzerland) · 2023Review
- Biomechanical Characteristics and Analysis Approaches of Bone and Bone Substitute Materials.Journal of functional biomaterials · 2023Review
- Article
- Percutaneous-Reinforced Osteoplasty: A Review of Emerging Treatment Strategies for Bone Interventions.Journal of clinical medicine · 2022Review
- Calcimimetics Alter Periosteal and Perilacunar Bone Matrix Composition and Material Properties in Early Chronic Kidney Disease.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022Article
- Osteocyte β1 integrin loss causes low bone mass and impairs bone mechanotransduction in mice.Journal of orthopaedic translation · 2022Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone is a nanocomposite material where the hard inorganic (hydroxyapatite crystallites) and organic (collagen fibrils) components are hierarchically arranged in the nanometer scale. Bone quality is dependent on the spatial distributions in the shape, size and composition of bone constituents (mineral, collagen and water). Bone hardness is an important property of bone, which includes both elastic and plastic deformation. In this study, a microhardness test was performed on a deer bone samples. The deer tibia shaft (diaphysis) was divided into several cross-sections of equal thickness; samples were prepared in untreated, boiled water treatment (100 °C for 30 min) and sodium hypochlorite (NaOCl) treatment conditions. Microhardness tests were performed on various regions of the tibial diaphysis to study the heterogeneous characteristics of bone microhardness and highlight the role of the organic matrix in bone hardness. The results indicated that boiled water treatment has a strong negative correlation with bone hardness. The untreated bone was significantly (+20%) harder than the boiled-water-treated bone. In general, the hardness values near the periosteal surface was significantly (23 to 45%) higher than the ones near the endosteal surface. Samples treated with NaOCl showed a significant reduction in hardness.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.