Evidence map›Paper›PMID 33271780›Full record

ReviewVaccines2020

Covid-19-Associated Pulmonary Aspergillosis: The Other Side of the Coin.

Claudio Costantini, Frank L van de Veerdonk, Luigina Romani

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Risk factors for identifying pulmonary aspergillosis in pediatric patients.Frontiers in cellular and infection microbiology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Performance of Two Commercial Assays for the Detection of SerumJournal of fungi (Basel, Switzerland) · 2022
    Article
  12. COVID-19 and Fungal Diseases.Antibiotics (Basel, Switzerland) · 2022
    Review
  13. Review
  14. Overview of COVID-19-Associated Invasive Fungal Infection.Current fungal infection reports · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Claudio CostantiniDepartment of Experimental Medicine, University of Perugia, 06132 Perugia, Italy.ORCID 0000-0002-1433-7830
Frank L van de VeerdonkDepartment of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Luigina RomaniDepartment of Experimental Medicine, University of Perugia, 06132 Perugia, Italy.
University of Perugia · ITRadboud University Nijmegen · NL

Funding

European Union's Horizon 2020 research and innovation program 847507
6 · The paper itself

Abstract

The immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a critical factor in the clinical presentation of COVID-19, which may range from asymptomatic to a fatal, multi-organ disease. A dysregulated immune response not only compromises the ability of the host to resolve the viral infection, but may also predispose the individual to secondary bacterial and fungal infections, a risk to which the current therapeutic immunomodulatory approaches significantly contribute. Among the secondary infections that may occur in COVID-19 patients, coronavirus-associated pulmonary aspergillosis (CAPA) is emerging as a potential cause of morbidity and mortality, although many aspects of the disease still remain unresolved. With this opinion, we present the current view of CAPA and discuss how the same mechanisms that underlie the dysregulated immune response in COVID-19 increase susceptibility to

Indexed as

anakinraAryl Hydrocarbon ReceptorAspergillusCOVID-19thymosin alpha 1

Identifiers

PMID33271780
PMCPMC7711593
OpenAlexW3107779368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.