ArticleMicromachines2020
A Lipid Bilayer Formed on a Hydrogel Bead for Single Ion Channel Recordings.
Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 9 citations in OpenAlex.
- Direct insertion of an ion channel immobilized on a soft agarose gel bead into a lipid bilayer: an optimized method.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Article
- Efficient single-channel current measurements of the human BK channel using a liposome-immobilized gold probe.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Article
- Characterizing the Structure and Interactions of Model Lipid Membranes Using Electrophysiology.Membranes · 2021Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Ion channel proteins play important roles in various cell functions, making them attractive drug targets. Artificial lipid bilayer recording is a technique used to measure the ion transport activities of channel proteins with high sensitivity and accuracy. However, the measurement efficiency is low. In order to improve the efficiency, we developed a method that allows us to form bilayers on a hydrogel bead and record channel currents promptly. We tested our system by measuring the activities of various types of channels, including gramicidin, alamethicin, α-hemolysin, a voltage-dependent anion channel 1 (VDAC1), a voltage- and calcium-activated large conductance potassium channel (BK channel), and a potassium channel from
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Registered trials
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