Evidence map›Paper›PMID 33271556›Full record

SynthesisDermatology (Basel, Switzerland)2021

Treatment Outcome Measurement Instruments for Port Wine Stains: A Systematic Review of Their Measurement Properties.

M Ingmar van Raath, Sandeep Chohan, Albert Wolkerstorfer, Chantal M A M van der Horst, Jacqueline Limpens, Xuan Huang, Baoyue Ding, Gert Storm, René R W J van der Hulst, Michal Heger

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Dermatology (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. COSMIN guideline for systematic reviews of patient-reported outcome measures version 2.0.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  4. Methodological quality of 100 recent systematic reviews of health-related outcome measurement instruments: an overview of reviews.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Development of a core outcome domain set for clinical research on capillary malformations (the COSCAM project).Journal of the European Academy of Dermatology and Venereology : JEADV · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

M Ingmar van RaathDepartment of Plastic, Reconstructive and Hand Surgery, Maastricht University Medical Center, Maastricht University, Maastricht, The Netherlands.
Sandeep ChohanDepartment of Dermatology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Albert WolkerstorferDepartment of Dermatology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Chantal M A M van der HorstDepartment of Plastic, Reconstructive and Hand Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Jacqueline LimpensMedical Library, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Xuan HuangDepartment of Pharmaceutics, Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, College of Medicine, Jiaxing University, Jiaxing, China.
Baoyue DingDepartment of Pharmaceutics, Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, College of Medicine, Jiaxing University, Jiaxing, China.
Gert StormDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
René R W J van der HulstDepartment of Plastic, Reconstructive and Hand Surgery, Maastricht University Medical Center, Maastricht University, Maastricht, The Netherlands.
Michal HegerDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands, E. m.heger@uu.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA plethora of outcome measurement instruments (OMIs) are being used in port wine stain (PWS) studies. It is currently unclear how valid, responsive, and reliable these are.

objectivesThe aim of this systematic review was to appraise the content validity and other measurement properties of OMIs for PWS treatment to identify the most appropriate instruments and future research priorities.

methodsThis study was performed using the updated Consensus-Based Standards for the Selection of Health Measurement Instruments (COSMIN) methodology and adhered to PRISMA guidelines. Comprehensive searches in Medline and Embase were performed. Studies in which an OMI for PWS patients was developed or its measurement properties were evaluated were included. Two investigators independently extracted data and assessed the quality of included studies and instruments to perform qualitative synthesis of the evidence.

resultsIn total, 1,034 articles were screened, and 77 full-text articles were reviewed. A total of 8 studies were included that reported on 6 physician-reported OMIs of clinical improvement and 6 parent- or patient-reported OMIs of life impact, of which 3 for health-related quality of life and 1 for perceived stigmatization. Overall, the quality of OMI development was inadequate (63%) or doubtful (37%). Each instrument has undergone a very limited evaluation in PWS patients. No content validity studies were performed. The quality of evidence for content validity was very low (78%), low (15%), or moderate (7%), with sufficient comprehensibility, mostly sufficient comprehensiveness, and mixed relevance. No studies on responsiveness, minimal important change, and cross-cultural validity were retrieved. There was moderate- to very low-quality evidence for sufficient inter-rater reliability for some clinical PWS OMIs. Internal consistency and measurement error were indeterminate in all studies.

conclusionsThere was insufficient evidence to properly guide outcome selection. Additional assessment of the measurement properties of OMIs is needed, preferentially guided by a core domain set tailored to PWS.

Indexed as

Outcome Assessment, Health CareHumansPort-Wine StainReproducibility of ResultsCapillary malformationClinical assessmentClinimetric studyPsychometric evaluationQuality of life

Identifiers

PMID33271556
PMCPMC8117375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.