Evidence map›Paper›PMID 33270989›Full record

Trial reportCancer medicine2021

Perioperative CRP: A novel inflammation-based classification in gastric cancer for recurrence and chemotherapy benefit.

Jun Lu, Bin-Bin Xu, Zhen Xue, Jian-Wei Xie, Chao-Hui Zheng, Chang-Ming Huang, Ping Li

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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  8. C-reactive protein and digestive pathologies: A narrative review for daily clinical use.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jun LuDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Bin-Bin XuDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Zhen XueDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Jian-Wei XieDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.ORCID 0000-0003-4971-2896
Chao-Hui ZhengDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.ORCID 0000-0003-0157-5167
Chang-Ming HuangDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.ORCID 0000-0002-0019-885X
Ping LiDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.ORCID 0000-0003-0332-867X
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerioperative C-reactive protein (CRP) levels have effects on the prognosis of cancer patients. We intended to determine the prognostic value of combining the two for gastric cancer (GC).

methodsData were extracted from a clinical trial. By calculating the area under the curve (AUC) and the C-index, the predictive value of CRPs among different time points, including preoperative (pre-CRP), postoperative days 1, 3, and 5 (post-CRPs), and postoperative maximum CRP (post-CRP

resultsFinally, 401 patients were available in the present study. For RFS, higher AUC (0.692) and concordance index (0.678) of pre-CRP were observed when compared with those of post-CRPs. Further, among post-CRPs, post-CRP

conclusionsBoth high-pre-CRP and high-post-CRP

Indexed as

GastrectomyNeoplasm Recurrence, LocalAgedBiomarkers, TumorChemotherapy, AdjuvantChinaC-Reactive ProteinFemaleHumansMaleMiddle AgedNeoplasm StagingPerioperative PeriodPredictive Value of TestsProgression-Free SurvivalRisk AssessmentBiomarkers, TumorC-Reactive Proteinadjuvant chemotherapyC-reactive proteingastric cancerprognosisrecurrence

Identifiers

PMID33270989
PMCPMC7826470
OpenAlexW3109710846

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.