Evidence map›Paper›PMID 33270765›Full record

ArticlePloS one2020

"It's because I think too much": Perspectives and experiences of adults with hypertension engaged in HIV care in northern Tanzania.

Preeti Manavalan, Linda Minja, Lisa Wanda, Julian T Hertz, Nathan M Thielman, Nwora Lance Okeke, Blandina T Mmbaga, Melissa H Watt

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Preeti ManavalanDivision of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0001-7587-224X
Linda MinjaKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Lisa WandaKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Julian T HertzDuke Global Health Institute, Durham, NC, United States of America.
Nathan M ThielmanDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.ORCID 0000-0001-8152-2879
Nwora Lance OkekeDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.
Blandina T MmbagaDuke Global Health Institute, Durham, NC, United States of America.ORCID 0000-0002-5550-1916
Melissa H WattDuke Global Health Institute, Durham, NC, United States of America.
Duke Institute for Health Innovation · USKilimanjaro Christian Medical Centre · TZDuke Medical Center · USUniversity of Florida · USUniversity of Utah · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI GEORGIA Doris TOMARAS · 2005 to 2026
$50.5M
Ruth L. Kirschstein National Research Service Award (NRSA)- T32T32AI007392 · NIAID · DUKE UNIVERSITY · PI Amy Lynn Corneli, Guido Ferrari · 1990 to 2026
$9.8M
Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
FIC NIH HHS D43 TW009337NIAID NIH HHS P30 AI064518NIAID NIH HHS T32 AI007392
6 · The paper itself

Abstract

backgroundHypertension, a leading risk for cardiovascular mortality, is an important co-morbidity among people living with HIV (PLHIV). In Tanzania, hypertension prevalence among PLHIV approaches 20 to 30%. However, most patients are unaware of their diagnosis and are not receiving treatment. Understanding the barriers to hypertension care is a critical first step in developing interventions to improve cardiovascular outcomes among PLHIV in Tanzania and similar settings.

methodsBetween September 1st and November 26th, 2018 thirteen semi structured in-depth interviews were conducted with hypertensive patients engaged in HIV care in two HIV clinics located in government health facilities in northern Tanzania. Interviews were audio-recorded, translated into English, transcribed and thematically coded using NVivo. Data analysis was conducted using applied thematic analysis.

resultsParticipants had a median age of 54 (IQR 41-65) years. Of the 13 participants, eight stated they had used antihypertensive medication previously, but only one participant described current use of antihypertensive therapy. All participants were currently using antiretroviral therapy. The data revealed a range of themes including limited hypertension knowledge. Universally, all participants believed that "thinking too much", i.e. stress, was the major contributor to hypertension and that by "reducing thoughts", one may control hypertension. Additional emerging themes included a perceived overlap between hypertension and HIV, delays in hypertension diagnosis and linkage to care, challenges with provider communication and counseling, reluctance towards antihypertensive medication, lack of integration of hypertension and HIV care, and additional structural barriers to hypertension care.

conclusionsParticipants described multiple, intersecting challenges related to hypertension management. Barriers specific to PLHIV included siloed care, HIV-related stigma, and burden from multiple medical conditions. Multifaceted strategies that seek to address structural barriers, hypertension education, psychosocial stressors and stigma, and that are integrated within HIV care are urgently needed to improve cardiovascular outcomes among PLHIV in sub-Saharan Africa.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultAgedAnti-HIV AgentsAntihypertensive AgentsCounselingFemaleHealth Services AccessibilityHIV InfectionsHumansHypertensionMaleMiddle AgedSocial StigmaTanzaniaAnti-HIV AgentsAntihypertensive Agents

Identifiers

PMID33270765
PMCPMC7714125
OpenAlexW3108164903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.