ArticlePLoS neglected tropical diseases2020
Vector competence of Aedes aegypti from Havana, Cuba, for dengue virus type 1, chikungunya, and Zika viruses.
Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Chikungunya Virus Mosquito Vectors: A Global Review of Field Surveillance and Laboratory Vector Competence (2020-2026).Insects · 2026Review
- Vector competence of Aedes albopictus from Northern, Southeastern, and Southern Brazil for locally circulating East-Central-South African and Asian genotypes of Chikungunya virus.PLoS neglected tropical diseases · 2026Article
- Re-emergence of chikungunya virus in the Caribbean: travel-associated cases imported from Cuba to France, 2025.Journal of travel medicine · 2026Article
- Detection of dengue virus serotypes in Aedes larvae: a multi-location study from Bhubaneswar, India, suggestive of vertical transmission.Virology journal · 2026Article
- Article
- The Effect of Increased Temperature on Dengue Virus in the VectorTropical medicine and infectious disease · 2026Article
- Vector competence of Aedes albopictus and Aedes aegypti from the islands of the Southwestern Indian Ocean for epidemic Zika, dengue, and chikungunya viruses.Parasites & vectors · 2025Article
- Beyond dengue and Oropouche: The urgent need for yellow fever preparedness in Cuba.New microbes and new infections · 2025Article
- Chikungunya virus: Current situation and future challenges.Biosafety and health · 2025Review
- The Frontier of Entomo-Virology: Applications and Tools for Virus and Vector Surveillance.Pathogens (Basel, Switzerland) · 2025Review
- Article
- Potential vectors associated to Oropouche virus transmission in Cuba, 2024.GigaByte (Hong Kong, China) · 2025Article
- An Update on the Entomology, Virology, Pathogenesis, and Epidemiology Status of West Nile and Dengue Viruses in Europe (2018-2023).Tropical medicine and infectious disease · 2024Review
- Ingestion of amoxicillin-clavulanic acid at therapeutic concentration during blood meal impacts Aedes aegypti microbiota and dengue virus transmission.Scientific reports · 2024Article
- DENV-1 Titer Impacts Viral Blocking inViruses · 2024Article
- Current Epidemiological Status of Chikungunya Virus Infection in East Africa: A Systematic Review and Meta-Analysis.Journal of tropical medicine · 2024Review
- Dengue as a Disease Threatening Global Health: A Narrative Review Focusing on Latin America and Brazil.Tropical medicine and infectious disease · 2023Review
- Diel activity patterns of vector mosquito species in the urban environment: Implications for vector control strategies.PLoS neglected tropical diseases · 2023Article
- Low Transmission of Chikungunya Virus by Aedes aegypti from Vientiane Capital, Lao PDRPathogens (Basel, Switzerland) · 2022Article
- Saliva collection via capillary method may underestimate arboviral transmission by mosquitoes.Parasites & vectors · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLike many countries from the Americas, Cuba is threatened by Aedes aegypti-associated arboviruses such as dengue (DENV), Zika (ZIKV), and chikungunya (CHIKV) viruses. Curiously, when CHIKV was actively circulating in the region in 2013-2014, no autochthonous transmission of this virus was detected in Havana, Cuba, despite the importation of chikungunya cases into this city. To investigate if the transmission ability of local mosquito populations could explain this epidemiological scenario, we evaluated for the first time the vector competence of two Ae. aegypti populations (Pasteur and Párraga) collected from Havana for dengue virus type 1 (DENV-1), CHIKV, and ZIKV. METHODOLOGY/PRINCIPAL
findingsMosquito populations were fed separately using blood containing ZIKV, DENV-1, or CHIKV. Infection, dissemination, and transmission rates, were estimated at 3 (exclusively for CHIKV), 7, and 14 days post exposure (dpe) for each Ae. aegypti population-virus combination. Both mosquito populations were susceptible to DENV-1 and ZIKV, with viral infection and dissemination rates ranging from 24-97% and 6-67% respectively. In addition, CHIKV disseminated in both populations and was subsequently transmitted. Transmission rates were low (<30%) regardless of the mosquito population/virus combination and no ZIKV was detected in saliva of females from the Pasteur population at any dpe. CONCLUSIONS/SIGNIFICANCE: Our study demonstrated the ability of Ae. aegypti from Cuba to transmit DENV, ZIKV, and CHIKV. These results, along with the widespread distribution and high abundance of this species in the urban settings throughout the island, highlight the importance of Ae. aegypti control and arbovirus surveillance to prevent future outbreaks.
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