Evidence map›Paper›PMID 33270497›Full record

ReviewHuman vaccines & immunotherapeutics2020

COVID-19 in the elderly people and advances in vaccination approaches.

Kuldeep Dhama, Shailesh Kumar Patel, Senthilkumar Natesan, Kranti Suresh Vora, Mohd Iqbal Yatoo, Ruchi Tiwari, Shailendra K Saxena, Karam Pal Singh, Rajendra Singh, Yashpal Singh Malik

Open access · greenAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly, Uttar Pradesh, India.ORCID 0000-0001-7469-4752
Shailesh Kumar PatelDivision of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly, Uttar Pradesh, India.
Senthilkumar NatesanDepartment of Infectious Diseases, Indian Institute of Public Health Gandhinagar , Ganghinagar, Gujarat, India.
Kranti Suresh VoraDepartment of Infectious Diseases, Indian Institute of Public Health Gandhinagar , Ganghinagar, Gujarat, India.ORCID 0000-0001-5999-1118
Mohd Iqbal YatooDivision of Veterinary Clinical Complex, Faculty of Veterinary Sciences and Animal Husbandry, Shuhama, Alusteng Srinagar, Sher-E-Kashmir University of Agricultural Sciences and Technology of Kashmir , Srinagar, Jammu and Kashmir, India.ORCID 0000-0002-4501-7354
Ruchi TiwariDepartment of Veterinary Microbiology and Immunology, College of Veterinary Sciences, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan (DUVASU) , Mathura, India.ORCID 0000-0001-6897-3472
Shailendra K SaxenaCentre for Advanced Research (CFAR), Faculty of Medicine, King George's Medical University (KGMU) , Lucknow, India.ORCID 0000-0003-2856-4185
Karam Pal SinghDivision of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly, Uttar Pradesh, India.
Rajendra SinghDivision of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly, Uttar Pradesh, India.ORCID 0000-0003-3127-3346
Yashpal Singh MalikDivision of Biological Standardization, ICAR-Indian Veterinary Research Institute , Bareilly, Uttar Pradesh, India.ORCID 0000-0002-2832-4854
Indian Veterinary Research Institute · INIndian Institute of Public Health Gandhinagar · INKing George's Medical University · INSher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir · INUniversity of Canberra · AUUttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid worldwide spread of the COVID-19 pandemic, caused by the newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in tens of millions of infections and over one million deaths. SARS-CoV-2 infection affects all age groups; however, those over 60 years old are affected more severely. Moreover, pre-existing co-morbidities result in higher COVID-19-associated mortality in the geriatric population. This article highlights the associated risk factors of SARS-CoV-2 infection in older people and progress in developing COVID-19 vaccines, especially for efficient vaccination of the older population. There is also a summary of immunomodulatory and immunotherapeutic approaches to ameliorate the outcome of COVID-19 in older individuals.

Indexed as

AgedAged, 80 and overClinical Trials as TopicCOVID-19COVID-19 VaccinesHumansVaccinationCOVID-19 Vaccinescovid-19elderly peopleSARS-CoV-2vaccine

Identifiers

PMID33270497
PMCPMC8641606
OpenAlexW3108639616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.