ArticleJournal of analytical toxicology2022
Toxic Metals in Liquid and Aerosol from Pod-Type Electronic Cigarettes.
Article in Journal of analytical toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- Electronic Smoking Devices Among University Students: Usage Patterns and Chemical Composition of Inhaled Substances.Analytical science advances · 2026Article
- Analytical investigation of metal distribution from e-cigarette aerosols to lung deposition using multi-platform mass spectrometry.Analytical and bioanalytical chemistry · 2026Article
- Molecular Health Effects of Electronic Cigarettes.Biomolecules · 2026Review
- A New Aerosol Respiratory Deposition Approach: Health Risks of Metals in Aerosols from Electronic Nicotine Delivery Systems and Heated Tobacco Products.Journal of aerosol science · 2026Article
- Analysing the acute toxicity of e-cigarette liquids and their vapour on human lung epithelial (A549) cellsToxicology reports · 2025Article
- Detection of Metal-Containing Particles in FDA-Authorized and New Disposable Electronic Cigarette Aerosols.Environmental science & technology · 2025Article
- Quantification of 16 Metals in Fluids and Aerosols From Ultrasonic Pod-Style Cigarettes and Comparison to Electronic Cigarettes.Environmental health perspectives · 2025Article
- Electronic Cigarette-Derived Metals: Exposure and Health Risks in Vapers.Chemical research in toxicology · 2025Review
- Review
- Pregnancy and Postpartum Effects of Electronic Cigarettes on Maternal Health and Vascular Function in the Fourth Trimester.Cardiovascular toxicology · 2025Article
- Multi-Omics Assessment of Puff Volume-Mediated Salivary Biomarkers of Metal Exposure and Oxidative Injury Associated with Electronic Nicotine Delivery Systems.Environmental health perspectives · 2025Article
- Article
- Maternal use of electronic cigarettes and impact on offspring: a double-hit model.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Quantification of Free Radicals from Vaping Electronic Cigarettes Containing Nicotine Salt Solutions with Different Organic Acid Types and Concentrations.Chemical research in toxicology · 2024Article
- In vitro toxicological evaluation of aerosols generated by a 4th generation vaping device using nicotine salts in an air-liquid interface system.Respiratory research · 2024Article
- Lactic Acid Salts of Nicotine Potentiate the Transfer of Toxic Metals into Electronic Cigarette Aerosols.Toxics · 2024Article
- Metal Concentrations in E-Cigarette Aerosol Samples: A Comparison by Device Type and Flavor.Environmental health perspectives · 2023Article
- Menthol flavoring in e-cigarette condensate causes pulmonary dysfunction and cytotoxicity in precision cut lung slices.American journal of physiology. Lung cellular and molecular physiology · 2023Article
- Toxicological Assessment of Particulate and Metal Hazards Associated with Vaping Frequency and Device Age.Toxics · 2023Article
- Determination of chemical constituent yields in e-cigarette aerosol using partial and whole pod collections, a comparative analysis.Frontiers in chemistry · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
High-quality, accurate data on liquid contents and aerosol emissions from electronic nicotine delivery systems (ENDS, e.g., e-cigarettes) are crucial to address potential health concerns as these devices evolve and mature. Metals are an important class of ENDS constituents that merit attention as they have various health implications. Proper sampling, handling and aerosol trapping materials are essential to generate accurate quantitative metal data and to reduce the likelihood of inaccurate results originating from inappropriate collection vessels and materials that contribute to high background levels. Published methods that meet these criteria were applied to the analyses of chromium, nickel, copper, zinc, cadmium, tin and lead in liquid and aerosol from mint/menthol and tobacco flavors of currently popular pod-based devices from three manufacturers. Metal concentrations from pods that had not been used for generating aerosol ranged from below our lowest reportable level to 0.164 µg/g for Cr, 61.3 µg/g for Ni, 927 µg/g for Cu, 14.9 µg/g for Zn, 58.2 µg/g for Sn and 2.56 µg/g for Pb. Cadmium was included in our analyte panel and was not present above detection limits in liquid or aerosol. Aerosol metal concentrations (using a 55-mL puff) ranged from below our lowest reportable level to 29.9 ng/10 puffs for Cr, 373 ng/10 puffs for Ni, 209 ng/10 puffs for Cu, 4,580 ng/10 puffs for Zn, 127 ng/10 puffs for Sn and 463 ng/10 puffs for Pb. Our results showed some metal delivery from all the products examined and highly variable metal levels between manufacturer, brand and package.
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Registered trials
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