Evidence map›Paper›PMID 33269596›Full record

ArticleACS sensors2020

Nanodiamond Relaxometry-Based Detection of Free-Radical Species When Produced in Chemical Reactions in Biologically Relevant Conditions.

Felipe Perona Martínez, Anggrek Citra Nusantara, Mayeul Chipaux, Sandeep Kumar Padamati, Romana Schirhagl

Open access · hybridAbstract read
In one paragraph

Article in ACS sensors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 108 citations in OpenAlex.

  1. Quantum biology: From mechanisms to medicine.Clinical and translational medicine · 2026
    Review
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  6. Quantum relaxometry for detecting biomolecular interactions with single NV centers.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. In Vivo Nanodiamond Quantum Sensing of Free Radicals in Caenorhabditis elegans Models.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Article
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  16. Free radical detection in precision-cut mouse liver slices with diamond-based quantum sensing.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Felipe Perona MartínezDepartment of Biomedical Engineering, University Medical Center Groningen, Groningen University, Antonius Deusinglaan 1, 9713 AW Groningen, The Netherlands.ORCID 0000-0001-8759-9586
Anggrek Citra NusantaraDepartment of Biomedical Engineering, University Medical Center Groningen, Groningen University, Antonius Deusinglaan 1, 9713 AW Groningen, The Netherlands.
Mayeul ChipauxInstitute of Physics, École Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Sandeep Kumar PadamatiDepartment of Biomedical Engineering, University Medical Center Groningen, Groningen University, Antonius Deusinglaan 1, 9713 AW Groningen, The Netherlands.
Romana SchirhaglDepartment of Biomedical Engineering, University Medical Center Groningen, Groningen University, Antonius Deusinglaan 1, 9713 AW Groningen, The Netherlands.ORCID 0000-0002-8749-1054
University Medical Center Groningen · NLÉcole Polytechnique Fédérale de Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diamond magnetometry is a quantum sensing method involving detection of magnetic resonances with nanoscale resolution. For instance, T1 relaxation measurements, inspired by equivalent concepts in magnetic resonance imaging (MRI), provide a signal that is equivalent to T1 in conventional MRI but in a nanoscale environment. We use nanodiamonds (between 40 and 120 nm) containing ensembles of specific defects called nitrogen vacancy (NV) centers. To perform a T1 relaxation measurement, we pump the NV center in the ground state (using a laser at 532 nm) and observe how long the NV center can remain in this state. Here, we use this method to provide real-time measurements of free radicals when they are generated in a chemical reaction. Specifically, we focus on the photolysis of H

Indexed as

NanodiamondsDiamondGadoliniumHydrogen PeroxideNitrogenDiamondGadoliniumHydrogen PeroxideNanodiamondsNitrogenbiochemical analysishydroxyl radicalmagnetometrynitrogen vacancy centerODMRrelaxometry

Identifiers

PMID33269596
PMCPMC8651177
OpenAlexW3106651428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.