ArticleWorld journal of clinical cases2020
Anterior bone loss after cervical disc replacement: A systematic review.
Article in World journal of clinical cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
- Coexistence of heterotopic ossification and anterior bone loss after multilevel cervical disc arthroplasty: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Rare Posterior Dislocation of Mobi-C Cervical Disc: A Case Report and Surgical Resolution.The American journal of case reports · 2025Article
- Anterior bone loss after anterior cervical discectomy and fusion: influence factors and its impact on surgical outcomes.BMC musculoskeletal disorders · 2025Article
- Bone resorption phenomenon following anterior-posterior combined cervical fusion surgery: is it a pathologic finding?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- The Future of Arthroplasty in the Spine.International journal of spine surgery · 2025Article
- Osteolysis after cervical disc arthroplasty with artificial cervical disc.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Clinical management of bone loss in cervical total disc arthroplasty: literature review and treatment recommendations.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Review
- More anterior bone loss in middle vertebra after contiguous two-segment cervical disc arthroplasty.Journal of orthopaedic surgery and research · 2024Article
- Anterior bone loss: A common phenomenon which should be considered as bone remodeling process existed not only in patients underwent cervical disk replacement but also those with anterior cervical diskectomy and fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Safety and Validity of Anterior Cervical Disc Replacement for Single-level Cervical Disc Disease: Initial Two-year Follow-up of the Prospective Observational Post-marketing Surveillance Study for Japanese Patients.Neurologia medico-chirurgica · 2022Observational
- Posterior intraprosthetic dislocation of cervical arthroplasty: illustrative case.Journal of neurosurgery. Case lessons · 2021Article
- The impact of smoking on outcomes following anterior cervical fusion-nonfusion hybrid surgery: a retrospective single-center cohort study.BMC musculoskeletal disorders · 2021Article
- National trends in post-operative complications for anterior cervical discectomy and fusion versus cervical disc arthroplasty from 2012 to 2022.Journal of craniovertebral junction & spineArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnterior bone loss (ABL) is a relatively easily neglected condition after cervical disc replacement (CDR). Whether this phenomenon is a radiological anomaly or a complication remains controversial. Several studies have reported the clinical characteristics of ABL and speculated on the pathogenic mechanism based on a certain type of artificial disc, while the overall understanding of ABL is lacking.
aimTo describe the prevalence, impacts, and risk factors of ABL after CDR.
methodsWe searched the PubMed, Cochrane Library, and Excerpta Medica databases using the terms "bone loss" or "bone remodeling" or "bone absorption" or "osteolysis" or "implant loosening" or "implant migration" or "hypersensitivity" or "hyperreactivity", "cervical disc replacement" or "cervical disc arthroplasty" or "total disc replacement". Eligible manuscripts on the prevalence and impacts of ABL were reviewed by the authors. Data extraction was performed using an established extraction form. The results of the included studies were described narratively.
resultsSix studies met the inclusion and exclusion criteria. One was a prospective study and the others were retrospective studies. A total of 440 patients with 536 segments were included. The artificial cervical discs included Bryan, Baguera-C, Discocerv, and Mobi-C. The prevalence of ABL ranged from 3.13% to 91.89%, with a combined overall prevalence of 41.84%. ABL occurred within 6 mo and stopped 12 mo after surgery. Several cases were noted to have a self-healing process. Severe ABL resulted in segmental kyphosis, implant subsidence, and persistent neck pain. ABL may be related to heterotopic ossification. Multilevel surgery may be one of the risk factors for ABL.
conclusionABL is a common condition after CDR. The underlying mechanisms of ABL may include stress concentration and injury to nutrient vessels. ABL should be considered a complication after CDR as it was associated with neck pain, implant subsidence, and heterotopic ossification.
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