Evidence map›Paper›PMID 33269099›Full record

ArticleAging and disease2020

Rationale and Methodology of The PopulatION HEalth and Eye Disease PRofile in Elderly Singaporeans Study [PIONEER].

Preeti Gupta, Ryan Eyn Kidd Man, Eva K Fenwick, Amudha Aravindhan, Alfred Tl Gan, Sahil Thakur, Bao Lin Pauline Soh, Joanne M Wood, Alex A Black, Angelique Chan and 10 more

Open access · goldAbstract read
In one paragraph

Article in Aging and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Revisiting the Osteoporosis Self-Assessment Tool (OST): evidence from a multi-cohort study in Asia supporting age-dependent thresholds.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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  7. The Association of Dietary Patterns with Age-Related Macular Degeneration in a Multiethnic Older Singaporean Population.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 2 countries.

Preeti Gupta1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Ryan Eyn Kidd Man1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Eva K Fenwick1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Amudha Aravindhan1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Alfred Tl Gan1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Sahil Thakur1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Bao Lin Pauline Soh3Singapore Institute of Technology, Health and Social Sciences, Singapore.
Joanne M Wood4Queensland University of Technology, Brisbane, Australia.
Alex A Black4Queensland University of Technology, Brisbane, Australia.
Angelique Chan2Duke-NUS Medical School, Singapore.
David Ng2Duke-NUS Medical School, Singapore.
Teoh Khim Hean5National Dental Centre, Singapore.
Edwin Goh5National Dental Centre, Singapore.
Chong Foong-Fong Mary6Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Jenny Loo7National University Hospital, Singapore.
Ciaran Gerard Forde8Singapore Institute for Clinical Sciences, National University of Singapore, Singapore.
Charumathi Sabanayagam1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Ching-Yu Cheng1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Tien Yin Wong1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Ecosse L Lamoureux1Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Duke-NUS Medical School · SGQueensland University of Technology · AUNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To describe the rationale, design and methodology of a geographically-representative and population-based study investigating the epidemiology, impact, personal and economic burden of age-related eye diseases, declining visual and other sensory systems in Asians aged >60 years in Singapore.PIONEER (The PopulatION HEalth and Eye Disease PRofilE in Elderly Singaporeans Study) is currently a cross-sectional study targeting 3152 Chinese, Malay and Indian adults who are Singapore citizens or permanent residents aged 60 years and older living across Singapore. The study is intended to be longitudinal, with several waves of data planned to be collected in the future. The sampling frame consisted of 7000 names derived from age, gender and ethnicity-stratified random sampling of individuals >60 years. Selected individuals were invited via letters, home visits, and telephone calls for a clinical assessment at the Singapore Eye Research Institute. Individuals with limited mobility were examined in a custom-designed mobile eye clinic. Questionnaires were subsequently administered at participants' homes by trained interviewers in their preferred language. A total of 3,299 participants (from East, West, North and South Singapore) were approached from December 2017 to November 2019. Of these, 953 (28.5%) were deemed ineligible. Out of 2,346 eligible participants, 904 (38.5%) refused, and 1,442 (61.5%) attended our clinical testing protocol, giving an initial response rate of 61.5%. Of these, 1,170 (81%) were cognitively able to complete the questionnaire assessment. The mean age±SD of our participants was 73.8±8.6 years; n=798 (55.3%) were female; and 828 (57.4%) were of Chinese ethnicity. The findings from this study will allow a deeper understanding of the risk factors and impact of aging in Asian populations, particularly in relation to the visual function and other functional system.

Indexed as

agingepidemiologyeye diseasepopulation-based studyvisual function systemvisual impairment

Identifiers

PMID33269099
PMCPMC7673841
OpenAlexW3108112428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.