Evidence map›Paper›PMID 33269003›Full record

ArticleJournal of pain research2020

Embodiment in Virtual Reality for the Treatment of Chronic Low Back Pain: A Case Series.

Michael S Trujillo, Anthony F Alvarez, Lincoln Nguyen, James Petros

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Journal of pain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05921747 (The Impact of Innovative Technology Strategies on Implementing Exercise Programs Using Fully Immersive Virtual Reality for Postpartum Women), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05921747 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

The Impact of Innovative Technology Strategies on Implementing Exercise Programs Using Fully Immersive Virtual Reality for Postpartum Women

TypeinterventionalSponsorShalamar Institute of Health SciencesRan2023 to 2026Enrolled34ConditionsPost Partum Lumbopelvic PainArmsTraditional exercise as control group, VR Intervention Group Protocol
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Virtual Reality Interventions and Chronic Pain: Scoping Review.Journal of medical Internet research · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Novel Therapies for Centralized Pain: a Brief Review.Current pain and headache reports · 2022
    Review
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  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael S TrujilloDepartment of Research, Karuna Labs, Inc, San Francisco, CA, USA.ORCID 0000-0001-6939-9388
Anthony F AlvarezDepartment of Research, Karuna Labs, Inc, San Francisco, CA, USA.ORCID 0000-0003-4006-1345
Lincoln NguyenDepartment of Research, Karuna Labs, Inc, San Francisco, CA, USA.
James PetrosDepartment of Research, Karuna Labs, Inc, San Francisco, CA, USA.
International Spine, Pain & Performance · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe describe two case studies that use embodiment in virtual reality as a treatment for chronic low back pain. The purpose of this case series was to determine the feasibility of a novel virtual reality-based digital therapeutic for the treatment of chronic pain. PATIENTS AND

methodsTwo patients with chronic low back pain received seven sessions, two sessions per week, of a novel digital therapeutic that combines virtual embodiment with graded motor imagery to deliver functional rehabilitation exercises using an off-the-shelf virtual reality system. Pain intensity was measured using a visual analog scale before and after each session to get an indication whether individual sessions of virtual embodiment training decrease pain intensity. Pain catastrophizing scale was assessed before the first session and after the seventh session to determine the extent to which virtual embodiment training can improve psychological symptoms of chronic low back pain.

resultsIn both patients, pain intensity was improved after individual sessions of virtual embodiment training as measured by a paired

conclusionThis case series provides evidence that embodiment in virtual reality improves symptoms of persistent chronic low back pain. We propose a mechanism by which virtual embodiment may improve chronic pain symptoms by recontextualizing sensory feedback from the body as patients engage in functional rehabilitation exercises while in virtual reality.

Indexed as

centralized paindigital therapeuticspain catastrophizing scalesensorimotorvisual analog scale

Identifiers

PMID33269003
PMCPMC7701139
OpenAlexW3110553665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.