Evidence map›Paper›PMID 33268998›Full record

ReviewDiabetes, metabolic syndrome and obesity : targets and therapy2020

Effect of Elevated Ketone Body on Maternal and Infant Outcome of Pregnant Women with Abnormal Glucose Metabolism During Pregnancy.

Meichen Qian, Na Wu, Ling Li, Wenshu Yu, Hong Ouyang, Xinyan Liu, Yujing He, Abdulrahman Al-Mureish

Open access · goldAbstract readReview
In one paragraph

Review in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. β-Hydroxybutyrate Exposure is Associated with Increased THCellular and molecular neurobiology · 2026
    Article
  3. Review
  4. The Ketogenic Diet in Obesity Management: Friend or Foe?Cell biochemistry and biophysics · 2026
    Review
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Diabetic Ketoacidosis in Pregnancy: A Systematic Review of the Reported Cases.Clinical medicine insights. Endocrinology and diabetes · 2025
    Review
  10. Review
  11. Article
  12. Does a Ketogenic Diet Have a Place Within Diabetes Clinical Practice? Review of Current Evidence and Controversies.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Review
  13. Review
  14. Euglycemic diabetic ketoacidosis in a pregnant woman.Journal of the American College of Emergency Physicians open · 2023
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Meichen QianDepartment of Endocrinology, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Na WuDepartment of Endocrinology, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Ling LiDepartment of Endocrinology, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Wenshu YuDepartment of Endocrinology, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Hong OuyangDepartment of Endocrinology, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Xinyan LiuDepartment of Endocrinology, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Yujing HeDepartment of Endocrinology, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.ORCID 0000-0002-0927-9728
Abdulrahman Al-MureishClinical Skills Practice Teaching Center, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ketone bodies are one of the products of fat metabolism which can be used as an alternative energy source for the human body in states of glucose deficiency. Normal pregnant women may develop ketosis due to physiological changes during pregnancy, while pregnant women with abnormal glucose metabolism are more likely to develop ketosis due to abnormal insulin secretion. Animal experiments and clinical studies have shown that exposure to high-ketone environments during pregnancy is closely related to adverse maternal and infant outcomes. However, there is no unified conclusion on whether ketone bodies should be routinely monitored during pregnancy. This review summarizes the existing studies on ketone body levels and pregnancy outcomes in the case of abnormal blood glucose during pregnancy, elaborates the current guidelines on the level of ketone bodies, provides the detection and treatment of ketosis in pregnant women with abnormal blood glucose in the clinical practice.

Indexed as

diabetes mellitusdiabetic ketoacidosisgestational diabetes mellitusketoacidosispregestational diabetes mellitus

Identifiers

PMID33268998
PMCPMC7701151
OpenAlexW3107342062

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.