Evidence map›Paper›PMID 33268969›Full record

ArticleWorld journal of gastroenterology2020

Crohn's disease in low and lower-middle income countries: A scoping review.

Ruma Rajbhandari, Samantha Blakemore, Neil Gupta, Alma J Adler, Christopher Allen Noble, Sara Mannan, Klejda Nikolli, Alison Yih, Sameer Joshi, Gene Bukhman

Abstract readScoping Review
In one paragraph

Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Inflammatory Bowel Disease in Children.Indian journal of pediatrics · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Engineered calprotectin-sensing probiotics for IBD surveillance in humans.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ruma RajbhandariDivision of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States.
Samantha BlakemoreDivision of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States.
Neil GuptaDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, MA 02199, United States.
Alma J AdlerDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, MA 02199, United States.
Christopher Allen NobleDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, MA 02199, United States.
Sara MannanDivision of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States.
Klejda NikolliDivision of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States.
Alison YihDivision of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States.
Sameer JoshiWestern Reserve Health Education, Trumbull Regional Medical Center, Warren, OH 44483, United States.
Gene BukhmanDivision of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile Crohn's disease has been studied extensively in high-income countries, its epidemiology and care in low and lower-middle income countries (LLMICs) is not well established due to a lack of disease registries and diagnostic capacity.

aimTo describe the published burden, diagnostic/treatment capacity, service utilization, challenges/barriers to individuals with Crohn's in LLMICs and their providers.

methodsWe conducted a scoping review utilizing a full search strategy was developed and conducted in PubMed, Embase and World Health Organization Global Index Medicus. Two independent reviewers screened the titles and abstracts of all of the publications found in this search, reviewed selected publications, and extracted relevant data, which underwent descriptive review and was analyzed in Excel.

resultsThe database search yielded 4486 publications, 216 of which were determined to be relevant to the research questions. Of all 79 LLMICs, only 21 (26.6%) have publications describing individuals with Crohn's. Overall, the highest number of studies came from India, followed by Tunisia, and Egypt. The mean number of Crohn's patients reported per study is 57.84 and the median is 22, with a wide range from one to 980.

conclusionThis scoping review has shown that, although there is a severe lack of population-based data about Crohn's in LLMICs, there is a signal of Crohn's in these settings around the world.

Indexed as

Crohn DiseaseDeveloping CountriesEgyptHumansIndiaRemission InductionTunisiaCrohn’s diseaseDiagnostic/Treatment capacityLow and lower-middle income countriesScoping reviewService utilization

Identifiers

PMID33268969
PMCPMC7684456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.