Evidence map›Paper›PMID 33268961›Full record

ArticleWorld journal of gastroenterology2020

Denise Sayuri Calheiros Silveira, Luciana Chain Veronez, Luís Carlos Lopes-Júnior, Elen Anatriello, Mariângela Ottoboni Brunaldi, Gabriela Pereira-da-Silva

Open access · greenAbstract read
In one paragraph

Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. The effects of dairy products containingFrontiers in nutrition · 2026
    Trial
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Article
  8. Bioactive materials · 2025
    Article
  9. Review
  10. Review
  11. Journal of gastrointestinal oncology · 2025
    Article
  12. Review
  13. Article
  14. Antioxidants (Basel, Switzerland) · 2024
    Article
  15. The Efficacy ofMetabolites · 2024
    Article
  16. Colorectal cancer and microbiota: systematic review.Przeglad gastroenterologiczny · 2024
    Review
  17. Review
  18. The Role of Probiotics in Colorectal Cancer: A Review.Journal of gastrointestinal cancer · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Denise Sayuri Calheiros SilveiraDepartment of Biochemistry and Immunology, University of São Paulo at Ribeirão Preto Medical School, Ribeirão Preto 14049-900, SP, Brazil.
Luciana Chain VeronezDepartment of Biochemistry and Immunology, University of São Paulo at Ribeirão Preto Medical School, Ribeirão Preto 14049-900, SP, Brazil.
Luís Carlos Lopes-JúniorHealth Sciences Center, Federal University of Espírito Santo - UFES, Vitória 29043-900, ES, Brazil.
Elen AnatrielloInstitute of Science and Technology, Federal University of São Paulo, UNIFESP, São José dos Campos 12231-280, SP, Brazil.
Mariângela Ottoboni BrunaldiDepartment of Pathology and Forensic Medicine, University of São Paulo, Ribeirão Preto 14040-902, SP, Brazil.
Gabriela Pereira-da-SilvaDepartment of Maternal-Infant Nursing and Public Health, University of São Paulo at Ribeirão Preto College of Nursing, Ribeirão Preto 14040-902, SP, Brazil. gbisson@eerp.usp.br.
Universidade de Ribeirão Preto · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Espírito Santo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColitis-associated cancer (CAC) accounts for 2%-3% of colorectal cancer (CRC) cases preceded by inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis. Intestinal microbiota has been reported to play a central role in the pathogenesis of IBD and CAC. Recently, numerous prebiotics and probiotics have being investigated as antitumor agents due to their capacity to modulate inflammatory responses. Previous studies have indicated that lactic acid bacteria could be successfully used in managing sporadic CRC, however little is known about their role in CAC.

aimTo investigate the effect of the probiotic

methodsC57BL/6 mice received an intraperitoneal injection of azoxymethane (10 mg/kg), followed by three cycles of sodium dextran sulphate diluted in water (5% w/v). Probiotic group received daily

results

conclusionOur results suggest a potential chemopreventive effect of probiotic on CAC.

Indexed as

ColitisColitis-Associated NeoplasmsLactobacillus delbrueckiiAnimalsAzoxymethaneColonDextran SulfateDisease Models, AnimalInflammationMiceMice, Inbred C57BLSulfatesAzoxymethaneDextran Sulfatesodium sulfateSulfatesCarcinogenesisColitis-associated cancerColorectal cancerInflammationLactobacillus bulgaricusProbiotics

Identifiers

PMID33268961
PMCPMC7684459
OpenAlexW3110504421

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.