Evidence map›Paper›PMID 33268894›Full record

ArticleNature2021

Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice.

Tomomi Karigo, Ann Kennedy, Bin Yang, Mengyu Liu, Derek Tai, Iman A Wahle, David J Anderson

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
24.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 197 citations in OpenAlex.

  1. Article
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  5. Review
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  7. The neural control of infanticide and parental behaviors in male mice.bioRxiv : the preprint server for biology · 2026
    Article
  8. Multispecies analysis of social effects on same-sex sexual behavior challenges mistaken identity hypotheses in insects.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. Article
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  16. Article
  17. Article
  18. Estrogen Control of Social Behaviors.Annual review of neuroscience · 2025
    Review
  19. Review
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tomomi KarigoDivision of Biology and Biological Engineering, TianQiao and Chrissy Chen Institute for Neuroscience, California Institute of Technology, Pasadena, CA, USA.
Ann KennedyDivision of Biology and Biological Engineering, TianQiao and Chrissy Chen Institute for Neuroscience, California Institute of Technology, Pasadena, CA, USA.ORCID http://orcid.org/0000-0002-3782-0518
Bin YangDivision of Biology and Biological Engineering, TianQiao and Chrissy Chen Institute for Neuroscience, California Institute of Technology, Pasadena, CA, USA.
Mengyu LiuDivision of Biology and Biological Engineering, TianQiao and Chrissy Chen Institute for Neuroscience, California Institute of Technology, Pasadena, CA, USA.
Derek TaiDivision of Biology and Biological Engineering, TianQiao and Chrissy Chen Institute for Neuroscience, California Institute of Technology, Pasadena, CA, USA.ORCID http://orcid.org/0000-0002-6461-5560
Iman A WahleDepartment of Computing and Mathematical Sciences, California Institute of Technology, Pasadena, CA, USA.
David J AndersonDivision of Biology and Biological Engineering, TianQiao and Chrissy Chen Institute for Neuroscience, California Institute of Technology, Pasadena, CA, USA. wuwei@caltech.edu.ORCID http://orcid.org/0000-0001-6175-3872
California Institute of Technology · USNorthwestern University · US

Funding

Generation of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI ZENG, HONGKUI · 2017 to 2021
$64.7M
Region-Specific, Inducible Axonal Tract-Tracing in the BrainR01MH070053 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI David J Anderson · 2004 to 2026
$9.7M
Molecular genetic dissection of central amygdala microcircuitry underlying fear aR01MH085082 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANDERSON, DAVID J · 2009 to 2019
$4.1M
Multimodal, integrated analysis of neural activity and naturalistic social behavior in freely moving miceR01MH123612 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANDERSON, DAVID J, PERONA, PIETRO · 2020 to 2024
$2.1M
Modeling a Neural Circuit for Flexible Control of Innate BehaviorsR00MH117264 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KENNEDY, ANN KATHRYN · 2021 to 2023
$742k
Modeling a neural circuit for flexible control of innate behaviorsK99MH117264 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KENNEDY, ANN KATHRYN · 2019 to 2020
$222k
Howard Hughes Medical InstituteNIMH NIH HHS K99 MH117264NIMH NIH HHS R00 MH117264NIMH NIH HHS R01 MH070053NIMH NIH HHS R01 MH085082NIMH NIH HHS R01 MH123612NIMH NIH HHS U19 MH114830
6 · The paper itself

Abstract

Animal behaviours that are superficially similar can express different intents in different contexts, but how this flexibility is achieved at the level of neural circuits is not understood. For example, males of many species can exhibit mounting behaviour towards same- or opposite-sex conspecifics

Indexed as

AggressionAnimalsCopulationEstrogen Receptor alphaFemaleHomosexuality, MaleHypothalamusMaleMiceOptogeneticsPreoptic AreaSexual Behavior, AnimalVesicular Inhibitory Amino Acid Transport ProteinsEstrogen Receptor alphaVesicular Inhibitory Amino Acid Transport Proteins

Identifiers

PMID33268894
PMCPMC7899581
OpenAlexW3107278778

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.