ReviewExperimental & molecular medicine2020
Shaping of the 3D genome by the ATPase machine cohesin.
Review in Experimental & molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Barrier effects on the kinetics of cohesin-mediated loop extrusion.Biophysical journal · 2025Article
- Co-essentiality analysis identifies PRR12 as a cohesin interacting protein and contributor to genomic integrity.Developmental cell · 2025Article
- PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation.The EMBO journal · 2024Article
- Regulating epithelial-mesenchymal plasticity from 3D genome organization.Communications biology · 2024Review
- Article
- Large-scale phenogenomic analysis of human cancers uncovers frequent alterations affecting SMC5/6 complex components in breast cancer.NAR cancer · 2023Article
- Symmetric control of sister chromatid cohesion establishment.Nucleic acids research · 2023Article
- Mechanisms of Long Non-Coding RNA in Breast Cancer.International journal of molecular sciences · 2023Review
- Cohesin and CTCF complexes mediate contacts in chromatin loops depending on nucleosome positions.Biophysical journal · 2022Article
- DecreasingScience advances · 2022Article
- CTCF and cohesin promote focal detachment of DNA from the nuclear lamina.Genome biology · 2022Article
- Characterizing the variation in chromosome structure ensembles in the context of the nuclear microenvironment.PLoS computational biology · 2022Article
- It's all in the numbers: Cohesin stoichiometry.Frontiers in molecular biosciences · 2022Review
- Role of circular RNAs in gastrointestinal tumors and drug resistance.World journal of clinical cases · 2021Review
- Sensitivity of cohesin-chromatin association to high-salt treatment corroborates non-topological mode of loop extrusion.Epigenetics & chromatin · 2021Article
- WAPL orchestrates porcine oocyte meiotic progression via control of spindle assembly checkpoint activity.Reproductive biology and endocrinology : RB&E · 2021Article
- Peripheral blood transcriptomics identifies cohesin-chromatin and immune dysregulation in tics and Tourette syndrome.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spatial organization of the genome is critical for fundamental biological processes, including transcription, genome replication, and segregation. Chromatin is compacted and organized with defined patterns and proper dynamics during the cell cycle. Aided by direct visualization and indirect genome reconstruction tools, recent discoveries have advanced our understanding of how interphase chromatin is dynamically folded at the molecular level. Here, we review the current understanding of interphase genome organization with a focus on the major regulator of genome structure, the cohesin complex. We further discuss how cohesin harnesses the energy of ATP hydrolysis to shape the genome by extruding chromatin loops.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.