Evidence map›Paper›PMID 33268807›Full record

ArticleScientific reports2020

Pistacia lentiscus extract enhances mammary epithelial cells' productivity by modulating their oxidative status.

O Hadaya, R Bransi-Nicola, Y Shalev, H Azaizeh, Z Roth, H Muklada, T Deutch, S Y Landau, N Argov-Argaman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Direct effects of phenolic compounds on the mammary gland:Food chemistry. Molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

O HadayaDepartment of Animal Sciences, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, 7610001, Rehovot, Israel.
R Bransi-NicolaThe Institute of Applied Research (Affiliated With University of Haifa), The Galilee Society, 20200, Shefa-Amr, Israel.
Y ShalevDepartment of Animal Sciences, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, 7610001, Rehovot, Israel.
H AzaizehThe Institute of Applied Research (Affiliated With University of Haifa), The Galilee Society, 20200, Shefa-Amr, Israel.
Z RothDepartment of Animal Sciences, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, 7610001, Rehovot, Israel.
H MukladaDepartment of Natural Resources, Institute of Plant Sciences, Agricultural Research Organization - the Volcani Center, 7505101, Rishon LeZion, Israel.
T DeutchDepartment of Natural Resources, Institute of Plant Sciences, Agricultural Research Organization - the Volcani Center, 7505101, Rishon LeZion, Israel.
S Y LandauDepartment of Natural Resources, Institute of Plant Sciences, Agricultural Research Organization - the Volcani Center, 7505101, Rishon LeZion, Israel.
N Argov-ArgamanDepartment of Animal Sciences, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, 7610001, Rehovot, Israel. argov.nurit@mail.huji.ac.il.
Hebrew University of Jerusalem · ILAgricultural Research Organization · ILUniversity of Haifa · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed the potential of phenolic compounds from Pistacia lentiscus (lentisk) to enhance production of milk constituents in bovine mammary epithelial cells (MEC). MEC were exposed to 0 (control), 1 or 10 ppm of polyphenols from lentisk ethanolic extract (PLEE) for 24 h. PLEE were absorbed by the MEC plasma membrane, but also penetrated the cell to accumulate in and around the nucleus. PLEE increased triglyceride content in the cell and its secretion to the medium, and significantly increased intracellular lipid droplet diameter. Compared to control, PLEE increased dose-dependently the lactose synthesis, secretion of whey proteins, and contents of casein. To evaluate mitochondrial activity under pro-oxidant load, MEC were preincubated with PLEE and exposed for 2 h to H

Indexed as

AnimalsCattleCells, CulturedEpithelial CellsFemaleGlycolipidsGlycoproteinsLactoseLipid DropletsLipid MetabolismMammary Glands, AnimalOxidation-ReductionOxygen ConsumptionPistaciaPlant ExtractsGlycolipidsGlycoproteinsLactosemilk fat globulePlant Extracts

Identifiers

PMID33268807
PMCPMC7710751
OpenAlexW3107508044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.