Evidence map›Paper›PMID 33268599›Full record

ArticleFukushima journal of medical science2020

Attempting to define sentinel node micrometastasis in oral squamous cell carcinoma.

Takashi Matsuzuka, Hirokazu Uemura, Seiichi Yoshimoto, Kouki Miura, Akihiro Shiotani, Masashi Sugasawa, Akihiro Homma, Junkichi Yokoyama, Kiyoaki Tsukahara, Tomokazu Yoshizaki and 5 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fukushima journal of medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 2 countries.

Takashi MatsuzukaDepartment of Head and Neck Surgery and Otolaryngology, Asahi University Hospital.
Hirokazu UemuraDepartment of Otolaryngology-Head and Neck Surgery, Nara Medical University.
Seiichi YoshimotoDepartment of Head and Neck Surgery, National Cancer Center Hospital.
Kouki MiuraDepartment of Head and Neck Oncology and Surgery, International University of Health and Welfare, Mita Hospital.
Akihiro ShiotaniDepartment of Otolaryngology-Head and Neck Surgery, National Defense Medical College.
Masashi SugasawaDepartment of Head and Neck Surgery, Saitama Medical University International Medical Center.
Akihiro HommaDepartment of Otolaryngology, Head and Neck Surgery, Hokkaido University Graduate School of Medicine.
Junkichi YokoyamaDepartment of Otolaryngology, Head and Neck Surgery, Moriyama Memorial Hospital.
Kiyoaki TsukaharaDepartment of Otolaryngology-Head and Neck Surgery, Tokyo Medical University Hospital.
Tomokazu YoshizakiDivision of Otolaryngology, Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University.
Yasushi YatabeDepartment of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital.
Takehiro KobariDepartment of Otolaryngology, Head and Neck Surgery, Fukushima Medical University.
Shigeru KosudaHealth Care Center, Kouseikai Hospital.
Shigeyuki MuronoDepartment of Otolaryngology, Head and Neck Surgery, Fukushima Medical University.
Yasuhisa HasegawaDepartment of Head and Neck Surgery and Otolaryngology, Asahi University Hospital.
Asahi University · JPFukushima Medical University · JPAichi Cancer Center · JPHokkaido University · JPKanazawa University · JPMita Hospital · JPNara Medical University · JPNational Cancer Center · USNational Defense Medical College · JPSaitama Medical University · JPSendai Kousei Hospital · JPTokyo Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this supplemental study of a sentinel node (SN) biopsy (SNB) trial for oral squamous cell carcinoma (OSCC) was to assess the effectiveness in identifying micrometastasis and determining whether elective neck dissection (END) is necessary. MATERIALS AND

methodsTwenty-three patients with pathologically positive SNs were included. The sizes of the metastatic lesions in positive SNs (SMSNs) were classified and the rates of occult metastasis of non-SNs were compared.

resultsThe patients were divided according to the SMSN:<0.2 mm (group A, n=3);0.2 mm to <2.0 mm (group B, n=7);and ≥2.0 mm (group C, n=13). The rates of occult metastasis in groups A, B, and C were 0% (0/3), 14% (1/7) and 23% (3/13), respectively.

conclusionRare cancer cell distribution to nodes other than SNs was observed in the patients with SN metastatic lesions of at least smaller than 0.2 mm in size, suggesting the possibility of defining SN micrometastasis in N0 OSCC.

Indexed as

Neoplasm MicrometastasisAdultAgedAged, 80 and overFemaleHumansLymphatic MetastasisMaleMiddle AgedMouth NeoplasmsSentinel Lymph NodeSquamous Cell Carcinoma of Head and Neckmicrometastasisoral squamous cell carcinomasentinel node

Identifiers

PMID33268599
PMCPMC7790463
OpenAlexW3106943016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.