ArticleBMC genomics2020
Moose genomes reveal past glacial demography and the origin of modern lineages.
Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 31 citations in OpenAlex.
- Bringing evolution into zoological parks through timetrees.Frontiers in bioinformatics · 2026Article
- Genomic Analyses Capture the Human-Induced Demographic Collapse and Recovery in a Wide-Ranging Cervid.Molecular biology and evolution · 2024Article
- Genomic insights into the Montseny brook newt (iScience · 2024Article
- Relationships of Late Pleistocene giant deer as revealed byiScience · 2023Article
- Range-wide and temporal genomic analyses reveal the consequences of near-extinction in Swedish moose.Communications biology · 2023Article
- Genomic Underpinnings of Population Persistence in Isle Royale Moose.Molecular biology and evolution · 2023Article
- Demography and evolutionary history of grey wolf populations around the Bering Strait.Molecular ecology · 2022Article
- Deep structure, long-distance migration and admixture in the colour polymorphic land snail Cepaea nemoralis.Journal of evolutionary biology · 2022Article
- Genetic evidence for post-glacial expansion from a southern refugium in the eastern moa (Biology letters · 2022Article
- Selection and demography drive range-wide patterns of MHC-DRB variation in mule deer.BMC ecology and evolution · 2022Article
- Phylogeographic relationships and the evolutionary history of the Carassius auratus complex with a newly born homodiploid raw fish (2nNCRC).BMC genomics · 2022Article
- CNVs with adaptive potential inLife science alliance · 2022Article
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Authors and funding
21 authors at 7 institutions in 4 countries.
Funding
Abstract
backgroundNumerous megafauna species from northern latitudes went extinct during the Pleistocene/Holocene transition as a result of climate-induced habitat changes. However, several ungulate species managed to successfully track their habitats during this period to eventually flourish and recolonise the holarctic regions. So far, the genomic impacts of these climate fluctuations on ungulates from high latitudes have been little explored. Here, we assemble a de-novo genome for the European moose (Alces alces) and analyse it together with re-sequenced nuclear genomes and ancient and modern mitogenomes from across the moose range in Eurasia and North America.
resultsWe found that moose demographic history was greatly influenced by glacial cycles, with demographic responses to the Pleistocene/Holocene transition similar to other temperate ungulates. Our results further support that modern moose lineages trace their origin back to populations that inhabited distinct glacial refugia during the Last Glacial Maximum (LGM). Finally, we found that present day moose in Europe and North America show low to moderate inbreeding levels resulting from post-glacial bottlenecks and founder effects, but no evidence for recent inbreeding resulting from human-induced population declines.
conclusionsTaken together, our results highlight the dynamic recent evolutionary history of the moose and provide an important resource for further genomic studies.
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