Evidence map›Paper›PMID 33267608›Full record

ArticleBiological research for nursing2021

Symptom Science: Omics and Response to Non-Pharmacological Interventions.

Monica A Wagner, Susan W Wesmiller, Meaghan Maydick, Lisa M Gawron, Frances M Peterson-Burch, Yvette P Conley

Open access · greenAbstract read
In one paragraph

Article in Biological research for nursing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Monica A WagnerSchool of Nursing, 6614University of Pittsburgh, PA, USA.ORCID 0000-0002-2707-6481
Susan W WesmillerSchool of Nursing, 6614University of Pittsburgh, PA, USA.
Meaghan MaydickSchool of Nursing, 6614University of Pittsburgh, PA, USA.
Lisa M GawronSchool of Nursing, 6614University of Pittsburgh, PA, USA.
Frances M Peterson-BurchSchool of Nursing, 6614University of Pittsburgh, PA, USA.
Yvette P ConleySchool of Nursing, 6614University of Pittsburgh, PA, USA.ORCID 0000-0002-1784-6067
University of Pittsburgh · US

Funding

Targeting Research and Academic Training of Nurses in GenomicsT32NR009759 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CONLEY, YVETTE P · 2006 to 2025
$4.5M
Omics of Pain in the Context of Declining EstrogenK99NR019080 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WAGNER, MONICA ANN · 2020 to 2021
$190k
NINR NIH HHS K99 NR019080NINR NIH HHS T32 NR009759
6 · The paper itself

Abstract

Incorporating omics into non-pharmacological intervention research design could provide a better understanding of the variability in response to these interventions. It would also provide evidence for precision-based non-pharmacological interventions, including interventions focused on symptoms. The purpose of this manuscript was to present examples of studies that have used omics to examine response to non-pharmacological intervention. Using the interventions of exercise, diet (related to obesity), cognitive based therapy, and alternative mind-body practices (meditation, yoga, and tai chi), PubMed was searched to identify studies that incorporated genomic or other omic approaches as part of a non-pharmacological intervention. The review identified genes associated with the effectiveness of each of the interventions. Although there were no genes that were associated with all four interventions, there were nine genes that were the focus of more than one intervention (

Indexed as

MeditationYogaCognitionExerciseHumansnon-pharmacological interventionomicssymptom science

Identifiers

PMID33267608
PMCPMC8755944
OpenAlexW3108654350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.