ArticleACS applied materials & interfaces2020
Highly Effective Inactivation of SARS-CoV-2 by Conjugated Polymers and Oligomers.
Article in ACS applied materials & interfaces, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Disinfection methods against SARS-CoV-2: a systematic review.The Journal of hospital infection · 2022Pooled it
- In Vitro Assessment ofGlobal challenges (Hoboken, NJ) · 2025Article
- Persistence of Coronavirus on Surface Materials and Its Control Measures Using Nonthermal Plasma and Other Agents.International journal of molecular sciences · 2023Review
- A Poly(carbazole-alt-triazole) with Thiabendazole Side Groups as an "On-Off-On" Fluorescent Probe for Detection of Cu(II) Ion and Cysteine.Journal of fluorescence · 2023Article
- Quaternary ammonium compounds of emerging concern: Classification, occurrence, fate, toxicity and antimicrobial resistance.Journal of hazardous materials · 2023Review
- Selective In Vitro and Ex Vivo Staining of Brain Neurofibrillary Tangles and Amyloid Plaques by Novel Ethylene Ethynylene-Based Optical Sensors.Biosensors · 2023Article
- A pH-Responsive Drug Delivery System Based on Conjugated Polymer for Effective Synergistic Chemo-/Photodynamic Therapy.Molecules (Basel, Switzerland) · 2023Article
- Development of Environmentally Friendly Biocidal Coatings Based on Water-soluble Copolymers for Air-cleaning Filters.ACS omega · 2022Article
- Macromolecular Viral Entry Inhibitors as Broad-Spectrum First-Line Antivirals with Activity against SARS-CoV-2.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Virucidal N95 Respirator Face Masks via Ultrathin Surface-Grafted Quaternary Ammonium Polymer Coatings.ACS applied materials & interfaces · 2022Article
- Transparent Anti-SARS-CoV-2 and Antibacterial Silver Oxide Coatings.ACS applied materials & interfaces · 2022Article
- Antiviral/antibacterial biodegradable cellulose nonwovens as environmentally friendly and bioprotective materials with potential to minimize microplastic pollution.Journal of hazardous materials · 2022Article
- Photodynamic Inactivation of Human Coronaviruses.Viruses · 2022Article
- Durable nanocomposite face masks with high particulate filtration and rapid inactivation of coronaviruses.Scientific reports · 2021Article
- What We Are Learning from COVID-19 for Respiratory Protection: Contemporary and Emerging Issues.Polymers · 2021Review
- Functionalized Masks: Powerful Materials against COVID-19 and Future Pandemics.Small (Weinheim an der Bergstrasse, Germany) · 2021Review
- The viability of SARS-CoV-2 on solid surfaces.Current opinion in colloid & interface science · 2021Review
- Article
- Antimicrobial Polymer-Based Assemblies: A Review.International journal of molecular sciences · 2021Review
- A Portrait of the OPE as a Biological Agent.Molecules (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
In the present study, we examined the inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by synthetic conjugated polymers and oligomers developed in our laboratories as antimicrobials for bacteria, fungi, and nonenveloped viruses. The results show highly effective light-induced inactivation with several of these oligomers and polymers including irradiation with near-UV and visible light. In the best case, one oligomer induced a 5-log reduction in pfu/mL within 10 min. In general, the oligomers are more active than the polymers; however, the polymers are active with longer wavelength visible irradiation. Although not studied quantitatively, the results show that in the presence of the agents at concentrations similar to those used in the light studies, there is essentially no dark inactivation of the virus. Because three of the five materials/compounds examined are quaternary ammonium derivatives, this study indicates that conventional quaternary ammonium antimicrobials may not be active against SARS-CoV-2. Our results suggest several applications involving the incorporation of these materials in wipes, sprays, masks, and clothing and other personal protection equipment that can be useful in preventing infections and the spreading of this deadly virus and future outbreaks from similar viruses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.