Evidence map›Paper›PMID 33266989›Full record

ArticleEntropy (Basel, Switzerland)2019

An Improved Method of Handling Missing Values in the Analysis of Sample Entropy for Continuous Monitoring of Physiological Signals.

Xinzheng Dong, Chang Chen, Qingshan Geng, Zhixin Cao, Xiaoyan Chen, Jinxiang Lin, Yu Jin, Zhaozhi Zhang, Yan Shi, Xiaohua Douglas Zhang

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Complexity analysis of head movements in autistic toddlers.Journal of child psychology and psychiatry, and allied disciplines · 2023
    Article
  5. Article
  6. Article
  7. Multiscale Entropy Approaches and Their Applications.Entropy (Basel, Switzerland) · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinzheng DongSchool of Software Engineering, South China University of Technology, Guangzhou 510006, China.ORCID 0000-0002-3734-4099
Chang ChenFaculty of Health Sciences, University of Macau, Taipa, Macau 999078, China.
Qingshan GengGuangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou 510080, China.
Zhixin CaoBeijing Engineering Research Center of Diagnosis and Treatment of Respiratory and Critical Care Medicine, Beijing Chaoyang Hospital, Beijing 100043, China.
Xiaoyan ChenDepartment of Endocrinology, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.
Jinxiang LinDepartment of Endocrinology, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.
Yu JinFaculty of Health Sciences, University of Macau, Taipa, Macau 999078, China.
Zhaozhi ZhangSchool of Law, Washington University, St. Louis, MO 63130, USA.
Yan ShiBeijing Engineering Research Center of Diagnosis and Treatment of Respiratory and Critical Care Medicine, Beijing Chaoyang Hospital, Beijing 100043, China.
Xiaohua Douglas ZhangFaculty of Health Sciences, University of Macau, Taipa, Macau 999078, China.ORCID 0000-0002-2486-7931

Funding

Universidade de Macau SRG2016-00083-FHS and FHS-CRDA-029-002-2017
6 · The paper itself

Abstract

Medical devices generate huge amounts of continuous time series data. However, missing values commonly found in these data can prevent us from directly using analytic methods such as sample entropy to reveal the information contained in these data. To minimize the influence of missing points on the calculation of sample entropy, we propose a new method to handle missing values in continuous time series data. We use both experimental and simulated datasets to compare the performance (in percentage error) of our proposed method with three currently used methods: skipping the missing values, linear interpolation, and bootstrapping. Unlike the methods that involve modifying the input data, our method modifies the calculation process. This keeps the data unchanged which is less intrusive to the structure of the data. The results demonstrate that our method has a consistent lower average percentage error than other three commonly used methods in multiple common physiological signals. For missing values in common physiological signal type, different data size and generating mechanism, our method can more accurately extract the information contained in continuously monitored data than traditional methods. So it may serve as an effective tool for handling missing values and may have broad utility in analyzing sample entropy for common physiological signals. This could help develop new tools for disease diagnosis and evaluation of treatment effects.

Indexed as

complexitymedical informationmissing valuesphysiological datasample entropy

Identifiers

PMID33266989
PMCPMC7514754

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.