ArticleCancers2020
MR Imaging Features to Differentiate Retinoblastoma from Coats' Disease and Persistent Fetal Vasculature.
Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Practical guidelines on imaging of retinoblastoma: a 2025 update on behalf of the European Retinoblastoma Imaging Collaboration and the European Retinoblastoma Group.European radiology · 2026Guideline
- Indications for Pediatric Enucleations of Non-Retinoblastoma Globes in Saudi Arabia with Clinical and Radiological Correlation To Final Histopathological Diagnosis.Journal of epidemiology and global health · 2025Article
- Retinoblastoma and beyond: pediatric orbital mass lesions.Neuroradiology · 2025Review
- A diagnostic dilemma: suspected retinoblastoma in a child from Sierra Leone.Eye (London, England) · 2024Article
- Coats' syndrome: A rare cause of infant leukocoria to keep in mind.Radiology case reports · 2024Article
- Changes in the incidence of early-onset breast cancer in Germany between 2010 and 2022.Breast cancer research and treatment · 2023Article
- MRI Features for IdentifyingRadiology · 2023Article
- Review
- Special Issue ofCancers · 2023Article
- [Imaging of retinoblastoma : Current state-of-the-art and future prospects].Radiologie (Heidelberg, Germany) · 2022Review
- Guidelines for magnetic resonance imaging in pediatric head and neck pathologies: a multicentre international consensus paper.Neuroradiology · 2022Article
- Dual-Target Multifunctional Superparamagnetic Cationic Nanoliposomes for Multimodal Imaging-Guided Synergistic Photothermal/Photodynamic Therapy of Retinoblastoma.International journal of nanomedicine · 2022Article
- Magnetic resonance imaging of the orbit, Part 2: Characterization of orbital pathologies.Indian journal of ophthalmology · 2021Review
- Cytomegalovirus Retinitis in an Eye with Unilateral Retinoblastoma: A Case Report.Case reports in ophthalmologyArticle
- Aqueous Humor Liquid Biopsy to Exclude Retinoblastoma for a Child with an Intraocular Mass.Case reports in ophthalmologyArticle
- Optic disc and peripapillary tumors.Taiwan journal of ophthalmologyReview
- Coats disease: A narrative review of clinical spectrum, imaging features, and contemporary management.Science progressReview
Corrections and comments
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Authors and funding
17 authors at 5 institutions in 5 countries.
Funding
Abstract
Retinoblastoma mimickers, or pseudoretinoblastoma, are conditions that show similarities with the pediatric cancer retinoblastoma. However, false-positive retinoblastoma diagnosis can cause mistreatment, while false-negative diagnosis can cause life-threatening treatment delay. The purpose of this study is to identify the MR imaging features that best differentiate between retinoblastoma and the most common pseudoretinoblastoma diagnoses: Coats' disease and persistent fetal vasculature (PFV). Here, six expert radiologists performed retrospective assessments (blinded for diagnosis) of MR images of patients with a final diagnosis based on histopathology or clinical follow-up. Associations between 20 predefined imaging features and diagnosis were assessed with exact tests corrected for multiple hypothesis testing. Sixty-six patients were included, of which 33 (50%) were retinoblastoma and 33 (50%) pseudoretinoblastoma patients. A larger eye size, vitreous seeding, and sharp-V-shaped retinal detachment were almost exclusively found in retinoblastoma (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.