Evidence map›Paper›PMID 33266210›Full record

ArticleVaccines2020

Type IIb Heat Labile Enterotoxin B Subunit as a Mucosal Adjuvant to Enhance Protective Immunity against H5N1 Avian Influenza Viruses.

Neos Tang, Chun-Yi Lu, Shih-Che Sue, Ting-Hsuan Chen, Jia-Tsrong Jan, Ming-Hsi Huang, Chung-Hsiung Huang, Chung-Chu Chen, Bor-Luen Chiang, Li-Min Huang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Neos TangInstitute of Biotechnology, National Tsing Hua University, Hsinchu 30013, Taiwan.
Chun-Yi LuDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei 100226, Taiwan.ORCID 0000-0002-5240-2808
Shih-Che SueInstitute of Bioinformatics and Structural Biology, Department of Life Science, National Tsing Hua University, Hsinchu 30013, Taiwan.ORCID 0000-0002-2169-0157
Ting-Hsuan ChenInstitute of Biotechnology, National Tsing Hua University, Hsinchu 30013, Taiwan.
Jia-Tsrong JanGenomics Research Center, Academia Sinica, Taipei 11529, Taiwan.
Ming-Hsi HuangNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan 35053, Taiwan.ORCID 0000-0002-9670-3821
Chung-Hsiung HuangDepartment of Food Science, National Taiwan Ocean University, Keelung 202301, Taiwan.ORCID 0000-0002-2295-6412
Chung-Chu ChenDepartment of Internal Medicine, MacKay Memorial Hospital, Hsinchu 30013, Taiwan; Taiwan.ORCID 0000-0003-4415-7811
Bor-Luen ChiangDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei 100226, Taiwan.
Li-Min HuangDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei 100226, Taiwan.ORCID 0000-0002-9291-260X
Suh-Chin WuInstitute of Biotechnology, National Tsing Hua University, Hsinchu 30013, Taiwan.
National Tsing Hua University · TWNational Taiwan University Hospital · TWGenomics Research Center, Academia Sinica · TWMinghsin University of Science and Technology · TWNational Health Research Institutes · TWNational Taiwan Ocean University · TW

Funding

Ministry of Science and Technology, Taiwan 109-2313-B-007-001
6 · The paper itself

Abstract

Human infections with highly pathogenic avian influenza H5N1 viruses persist as a major global health concern. Vaccination remains the primary protective strategy against H5N1 and other novel avian influenza virus infections. We investigated the use of

Indexed as

H5N1 vaccineintranasal immunizationLTIIb-B5mucosal adjuvant

Identifiers

PMID33266210
PMCPMC7768441
OpenAlexW3108316982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.