Evidence map›Paper›PMID 33266167›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Convolutional Neural Network-Based Humerus Segmentation and Application to Bone Mineral Density Estimation from Chest X-ray Images of Critical Infants.

Yung-Chun Liu, Yung-Chieh Lin, Pei-Yin Tsai, Osuke Iwata, Chuew-Chuen Chuang, Yu-Han Huang, Yi-Shan Tsai, Yung-Nien Sun

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Yung-Chun LiuDepartment of Biomedical Engineering, Da-Yeh University, Changhua 51591, Taiwan.ORCID 0000-0002-0949-6917
Yung-Chieh LinDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng-Kung University, Tainan 70457, Taiwan.ORCID 0000-0002-7698-8428
Pei-Yin TsaiDepartment of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng-Kung University, Tainan 70457, Taiwan.
Osuke IwataDepartment of Neonatology and Pediatrics, Nagoya City University Graduate School of Medical Science, Nagoya, Aichi 467-8601, Japan.ORCID 0000-0001-9277-1109
Chuew-Chuen ChuangDepartment of Computer Science & Information Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Yu-Han HuangDepartment of Computer Science & Information Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Yi-Shan TsaiDepartment of Medical Imaging, National Cheng Kung University Hospital, College of Medicine, National Cheng-Kung University, Tainan 70457, Taiwan.
Yung-Nien SunDepartment of Computer Science & Information Engineering, National Cheng Kung University, Tainan 701, Taiwan.
National Cheng Kung University Hospital · TWNational Cheng Kung University · TWDayeh University · TWNagoya City University · JPNational Science and Technology Council · TW

Funding

Ministry of Science and Technology, Taiwan 109-2634-F-006-012Ministry of Science and Technology, Taiwan 109-2634-F-006-019
6 · The paper itself

Abstract

Measuring bone mineral density (BMD) is important for surveying osteopenia in premature infants. However, the clinical availability of dual-energy X-ray absorptiometry (DEXA) for standard BMD measurement is very limited, and it is not a practical technique for critically premature infants. Developing alternative approaches for DEXA might improve clinical care for bone health. This study aimed to measure the BMD of premature infants via routine chest X-rays in the intensive care unit. A convolutional neural network (CNN) for humeral segmentation and quantification of BMD with calibration phantoms (QRM-DEXA) and soft tissue correction were developed. There were 210 X-rays of premature infants evaluated by this system, with an average Dice similarity coefficient value of 97.81% for humeral segmentation. The estimated humerus BMDs (g/cm

Indexed as

bone mineral densitydeep learningosteopenia of prematuritypremature infantsricketsX-ray segmentation

Identifiers

PMID33266167
PMCPMC7759858
OpenAlexW3108394269

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.