Evidence map›Paper›PMID 33266068›Full record

ArticleInternational journal of molecular sciences2020

Effectiveness in Block by Dexmedetomidine of Hyperpolarization-Activated Cation Current, Independent of Its Agonistic Effect on α

Te-Ling Lu, Te-Jung Lu, Sheng-Nan Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  9. Editorial to the Special Issue "Electrophysiology".International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Te-Ling LuSchool of Pharmacy, China Medical University, Taichung City 406040, Taiwan.ORCID 0000-0003-1408-6004
Te-Jung LuDepartment of Medical Laboratory Science and Biotechnology, Chung Hwa University of Medical Technology, Tainan City 71703, Taiwan.
Sheng-Nan WuDepartment of Medical Research, China Medical University Hospital, China Medical University, Taichung City 40402, Taiwan.ORCID 0000-0002-5208-3253
Chung Hwa University of Medical Technology · TWChina Medical University · TW

Funding

China Medical University, Taiwan CMU101-ASIA-07Ministry of Education D108-F2507Ministry of Science and Technology, Taiwan MOST-108-2314-B-006-094National Cheng Kung University D107-F2519 and NCKUH-10709001
6 · The paper itself

Abstract

Dexmedetomidine (DEX), a highly selective agonist of α

Indexed as

Action PotentialsAdrenergic alpha-2 Receptor AgonistsAnimalsCell Line, TumorDexmedetomidineHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIon Channel GatingIvabradineOxaliplatinPC12 CellsPotassium ChannelsRatsReceptors, Adrenergic, alpha-2YohimbineAdrenergic alpha-2 Receptor AgonistsDexmedetomidineHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIvabradineOxaliplatinPotassium ChannelsReceptors, Adrenergic, alpha-2Yohimbineaction potentialdexmedetomidineendocrine cellshyperpolarization-activated cation currentvoltage hysteresis

Identifiers

PMID33266068
PMCPMC7730867
OpenAlexW3108017860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.