Evidence map›Paper›PMID 33266058›Full record

ArticleNutrients2020

Understanding the Heterogeneity of Obesity and the Relationship to the Brain-Gut Axis.

Tony K W Hung, Tien S Dong, Zixi Chen, David Elashoff, Janet S Sinsheimer, Jonathan P Jacobs, Venu Lagishetty, Priten Vora, Jean Stains, Emeran A Mayer and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Tony K W HungDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.
Tien S DongDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0003-0105-8063
Zixi ChenDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.
David ElashoffDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.
Janet S SinsheimerDepartment of Computational Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.ORCID 0000-0001-9540-5956
Jonathan P JacobsDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0003-4698-0254
Venu LagishettyDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0001-6500-8255
Priten VoraDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.
Jean StainsDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.
Emeran A MayerDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.
Arpana GuptaDivision of Hematology and Oncology, University of California, Los Angeles, CA 90095, USA.
University of California, Los Angeles · US

Funding

PERCEPTION AND MODULATION OF VISCERAL SENSATIONSR01DK048351 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYER, EMERAN A · 1996 to 2019
$8.2M
Modulation of the Intestinal Microbiome in Obesity by a High Protein DietIK2CX001717 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI JACOBS, JONATHAN PATRICK · 2018 to 2023
–
Ahmanson-Lovelace Brain Mapping Center Pilot funds provided for brain scanningCSRD VA IK2 CX001717NIH HHS K23 105628NIH HHS R01 DK048351UCLA CURE/CTSI Pilot and Feasibility Study ULTR001881/DK041301VA IK2CX001717
6 · The paper itself

Abstract

Obesity is best understood as a multifactorial metabolic imbalances disorder. In a cross-sectional study, we aimed to explore sociodemographic and dietary determinants of obesity in relation to brain-gut homeostasis among overweight and obese individuals. Multivariate logistic regression models were used to examine obesity and its association with sociodemographic and dietary factors. Biological variables examined included the gut microbiome, fecal amino acid metabolites and brain structural volumes. Among 130 participants, there were higher odds of obesity if individuals were Hispanic (adjusted odds ratio (aOR) 1.56,

Indexed as

AdolescentAdultAmino AcidsBody Mass IndexBrainCross-Sectional StudiesDietFecesFemaleGastrointestinal MicrobiomeGastrointestinal TractHispanic or LatinoHumansMaleMetabolic DiseasesMiddle AgedAmino AcidsRNA, Ribosomal, 16Samino acidsbrain-gut axisdiethealth disparityheterogeneityHispanicmetabolitesmicrobiomeobesityprecision medicine

Identifiers

PMID33266058
PMCPMC7761087
OpenAlexW3108477384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.