Evidence map›Paper›PMID 33265981›Full record

ArticleMolecules (Basel, Switzerland)2020

Shock Processing of Amino Acids Leading to Complex Structures-Implications to the Origin of Life.

Surendra V Singh, Jayaram Vishakantaiah, Jaya K Meka, Vijayan Sivaprahasam, Vijayanand Chandrasekaran, Rebecca Thombre, Vijay Thiruvenkatam, Ambresh Mallya, Balabhadrapatruni N Rajasekhar, Mariyappan Muruganantham and 7 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Surendra V SinghAtomic Molecular and Optical Physics Division, Physical Research Laboratory, Ahmedabad 380009, India.ORCID 0000-0001-5982-8433
Jayaram VishakantaiahSolid State & Structural Chemistry Unit, Indian Institute of Science, Bangalore 560012, India.
Jaya K MekaAtomic Molecular and Optical Physics Division, Physical Research Laboratory, Ahmedabad 380009, India.
Vijayan SivaprahasamPlanetary Science Division, Physical Research Laboratory, Ahmedabad 380009, India.ORCID 0000-0002-1028-8074
Vijayanand ChandrasekaranDepartment of Chemistry, Vellore Institute of Technology, Vellore 632014, India.ORCID 0000-0002-8314-8611
Rebecca ThombreDepartment of Biotechnology, Modern College of Arts, Science and Commerce, Pune 411005, India.
Vijay ThiruvenkatamDiscipline of Biological Engineering, Indian Institute of Technology Gandhinagar, Gandhinagar 382355, India.
Ambresh MallyaCentre for Nano Science and Engineering, Indian Institute of Science, Bangalore 560012, India.
Balabhadrapatruni N RajasekharAtomic and Molecular Physics Division, BARC, Trombay, Mumbai 400085, India.
Mariyappan MurugananthamGeosciences Division, Physical Research Laboratory, Ahmedabad 380009, India.
Akshay DateyDepartment of Aerospace Engineering, Indian Institute of Science, Bangalore 560012, India.
Hugh HillPhysical Sciences, International Space University, 67400 Illkirch-Graffenstaden, France.
Anil BhardwajPlanetary Science Division, Physical Research Laboratory, Ahmedabad 380009, India.ORCID 0000-0003-1693-453X
Gopalan JagadeeshDepartment of Aerospace Engineering, Indian Institute of Science, Bangalore 560012, India.
Kalidevapura P J ReddyDepartment of Aerospace Engineering, Indian Institute of Science, Bangalore 560012, India.
Nigel J MasonSchool of Physical Sciences, University of Kent, Canterbury CT2 7NZ, UK.
Bhalamurugan SivaramanAtomic Molecular and Optical Physics Division, Physical Research Laboratory, Ahmedabad 380009, India.
Physical Research Laboratory · INIndian Institute of Science Bangalore · INBhabha Atomic Research Centre · INIndian Institute of Technology Gandhinagar · INInternational Space University · FRUniversity of Kent · GBVellore Institute of Technology University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The building blocks of life, amino acids, are believed to have been synthesized in the extreme conditions that prevail in space, starting from simple molecules containing hydrogen, carbon, oxygen and nitrogen. However, the fate and role of amino acids when they are subjected to similar processes largely remain unexplored. Here we report, for the first time, that shock processed amino acids tend to form complex agglomerate structures. Such structures are formed on timescales of about 2 ms due to impact induced shock heating and subsequent cooling. This discovery suggests that the building blocks of life could have self-assembled not just on Earth but on other planetary bodies as a result of impact events. Our study also provides further experimental evidence for the 'threads' observed in meteorites being due to assemblages of (bio)molecules arising from impact-induced shocks.

Indexed as

Earth, PlanetMeteoroidsOrigin of LifeAmino AcidsMacromolecular SubstancesAmino AcidsMacromolecular Substancesamino acidsastrobiologycomplex structuresorigin of lifeshock processing

Identifiers

PMID33265981
PMCPMC7730583
OpenAlexW3108683272

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.