Evidence map›Paper›PMID 33265972›Full record

ArticleTropical medicine and infectious disease2020

Optimizing Active Tuberculosis Case Finding: Evaluating the Impact of Community Referral for Chest X-ray Screening and Xpert Testing on Case Notifications in Two Cities in Viet Nam.

Tuan Huy Mac, Thuc Huy Phan, Van Van Nguyen, Thuy Thu Thi Dong, Hoi Van Le, Quan Duc Nguyen, Tho Duc Nguyen, Andrew James Codlin, Thuy Doan To Mai, Rachel Jeanette Forse and 9 more

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 27 citations in OpenAlex.

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  12. Cost-effectiveness of Low-complexity Screening Tests in Community-based Case-finding for Tuberculosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Tuan Huy MacHai Phong Lung Hospital, Hai Phong 180000, Vietnam.
Thuc Huy PhanProvincial Department of Health, Hai Phong 180000, Vietnam.
Van Van NguyenProvincial Department of Health, Quang Nam 560000, Vietnam.
Thuy Thu Thi DongFriends for International TB Relief, Ha Noi 100000, Vietnam.
Hoi Van LeViet Nam National Lung Hospital, Ha Noi 100000, Vietnam.
Quan Duc NguyenProvincial Department of Health, Hai Phong 180000, Vietnam.
Tho Duc NguyenHai Phong Lung Hospital, Hai Phong 180000, Vietnam.
Andrew James CodlinFriends for International TB Relief, Ha Noi 100000, Vietnam.
Thuy Doan To MaiFriends for International TB Relief, Ha Noi 100000, Vietnam.
Rachel Jeanette ForseFriends for International TB Relief, Ha Noi 100000, Vietnam.
Lan Phuong NguyenFriends for International TB Relief, Ha Noi 100000, Vietnam.
Tuan Ho Thanh LuuClinton Health Access Initiative, Ha Noi 100000, Vietnam.ORCID 0000-0001-9492-2337
Hoa Binh NguyenViet Nam National Lung Hospital, Ha Noi 100000, Vietnam.
Nhung Viet NguyenViet Nam National Lung Hospital, Ha Noi 100000, Vietnam.
Xanh Thu PhamProvincial Department of Health, Hai Phong 180000, Vietnam.
Phap Ngoc TranPham Ngoc Thach Quang Nam Hospital, Quang Nam 560000, Vietnam.
Amera KhanStop TB Partnership, 1218 Geneva, Switzerland.ORCID 0000-0002-4052-2028
Luan Nguyen Quang VoFriends for International TB Relief, Ha Noi 100000, Vietnam.ORCID 0000-0002-5937-6286
Jacob CreswellStop TB Partnership, 1218 Geneva, Switzerland.ORCID 0000-0002-4885-940X
Hai Phong University · VNHanoi Lung Hospital · VN

Funding

Global Affairs Canada W5_VNM_CDT2_NTP
6 · The paper itself

Abstract

To accelerate the reduction in tuberculosis (TB) incidence, it is necessary to optimize the use of innovative tools and approaches available within a local context. This study evaluated the use of an existing network of community health workers (CHW) for active case finding, in combination with mobile chest X-ray (CXR) screening events and the expansion of Xpert MTB/RIF testing eligibility, in order to reach people with TB who had been missed by the current system. A controlled intervention study was conducted from January 2018 to March 2019 in five intervention and four control districts of two low to medium TB burden cities in Viet Nam. CHWs screened and referred eligible persons for CXR to TB care facilities or mobile screening events in the community. The initial diagnostic test was Xpert MTB/RIF for persons with parenchymal abnormalities suggestive of TB on CXR or otherwise on smear microscopy. We analyzed the TB care cascade by calculating the yield and number needed to screen (NNS), estimated the impact on TB notifications and conducted a pre-/postintervention comparison of TB notification rates using controlled, interrupted time series (ITS) analyses. We screened 30,336 individuals in both cities to detect and treat 243 individuals with TB, 88.9% of whom completed treatment successfully. All forms of TB notifications rose by +18.3% (95% CI: +15.8%, +20.8%). The ITS detected a significant postintervention step-increase in the intervention area for all-form TB notification rates (IRR(β6) = 1.221 (95% CI: 1.011, 1.475);

Indexed as

active case findingcommunity health workersmobile X-ray screeningtuberculosis

Identifiers

PMID33265972
PMCPMC7709663
OpenAlexW3109290351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.