Evidence map›Paper›PMID 33265930›Full record

ArticleVaccines2020

Bacterial Immunogenicity Prediction by Machine Learning Methods.

Ivan Dimitrov, Nevena Zaharieva, Irini Doytchinova

Abstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  14. SHASI-ML: a machine learning-based approach for immunogenicity prediction inFrontiers in cellular and infection microbiology · 2025
    Article
  15. Review
  16. Viral Immunogenicity Prediction by Machine Learning Methods.International journal of molecular sciences · 2024
    Article
  17. Review
  18. Review
  19. Prediction of Bacterial Immunogenicity by Machine Learning Methods.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ivan DimitrovFaculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria.ORCID 0000-0003-4838-312X
Nevena ZaharievaFaculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria.
Irini DoytchinovaFaculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria.ORCID 0000-0002-1469-1768

Funding

Bulgarian National Roadmap for Research Infrastructure (2017-2023) D01-271/2019Science and Education for Smart Growth Operational Program (2014-2020) BG05M2OP001-1.001-0003
6 · The paper itself

Abstract

The identification of protective immunogens is the most important and vigorous initial step in the long-lasting and expensive process of vaccine design and development. Machine learning (ML) methods are very effective in data mining and in the analysis of big data such as microbial proteomes. They are able to significantly reduce the experimental work for discovering novel vaccine candidates. Here, we applied six supervised ML methods (partial least squares-based discriminant analysis,

Indexed as

immunogenicity predictionmachine learningprotective immunogens

Identifiers

PMID33265930
PMCPMC7711804

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.