Evidence map›Paper›PMID 33265493›Full record

ReviewEntropy (Basel, Switzerland)2018

Entropy Change of Biological Dynamics in Asthmatic Patients and Its Diagnostic Value in Individualized Treatment: A Systematic Review.

Shixue Sun, Yu Jin, Chang Chen, Baoqing Sun, Zhixin Cao, Iek Long Lo, Qi Zhao, Jun Zheng, Yan Shi, Xiaohua Douglas Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Entropy (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Shixue SunFaculty of Health Sciences, University of Macau, Taipa, Macau, China.ORCID 0000-0002-0929-977X
Yu JinFaculty of Health Sciences, University of Macau, Taipa, Macau, China.ORCID 0000-0002-3290-3293
Chang ChenFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
Baoqing SunState Key Laboratory of Respiratory Disease, the 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou 510230, China.
Zhixin CaoBeijing Engineering Research Center of Diagnosis and Treatment of Respiratory and Critical Care Medicine, Beijing Chaoyang Hospital, Beijing 100043, China.
Iek Long LoDepartment of Geriatrics, Centro Hospital Conde de Sao Januario, Macau, China.
Qi ZhaoFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
Jun ZhengFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
Yan ShiDepartment of Mechanical and Electronic Engineering, Beihang University, Beijing 100191, China.
Xiaohua Douglas ZhangFaculty of Health Sciences, University of Macau, Taipa, Macau, China.ORCID 0000-0002-2486-7931
University of Macau · MOBeihang University · CNBeijing Chaoyang Emergency Medical Center · CNHospital Conde S. Januário · CNState Key Laboratory of Respiratory Disease · CN

Funding

Fundo para o Desenvolvimento das Ciências e da Tecnologia FDCT/131/2016/A3University of Macau FHS Research Grant FHS-CRDA-029-002-2017University of Macau Start-up Research Grant SRG2016-00083-FHS
6 · The paper itself

Abstract

Asthma is a chronic respiratory disease featured with unpredictable flare-ups, for which continuous lung function monitoring is the key for symptoms control. To find new indices to individually classify severity and predict disease prognosis, continuous physiological data collected from monitoring devices is being studied from different perspectives. Entropy, as an analysis method for quantifying the inner irregularity of data, has been widely applied in physiological signals. However, based on our knowledge, there is no such study to summarize the complexity differences of various physiological signals in asthmatic patients. Therefore, we organized a systematic review to summarize the complexity differences of important signals in patients with asthma. We searched several medical databases and systematically reviewed existing asthma clinical trials in which entropy changes in physiological signals were studied. As a conclusion, we find that, for airflow, heart rate variability, center of pressure and respiratory impedance, their entropy values decrease significantly in asthma patients compared to those of healthy people, while, for respiratory sound and airway resistance, their entropy values increase along with the progression of asthma. Entropy of some signals, such as respiratory inter-breath interval, shows strong potential as novel indices of asthma severity. These results will give valuable guidance for the utilization of entropy in physiological signals. Furthermore, these results should promote the development of management and diagnosis of asthma using continuous monitoring data in the future.

Indexed as

asthmaentropyindividualized treatmentirregularityphysiological signal

Identifiers

PMID33265493
PMCPMC7512921
OpenAlexW2804227225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.