Evidence map›Paper›PMID 33265245›Full record

ArticleEntropy (Basel, Switzerland)2018

Multivariate Entropy Characterizes the Gene Expression and Protein-Protein Networks in Four Types of Cancer.

Angel Juarez-Flores, Marco V José

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Angel Juarez-FloresPosgrado en Ciencias Biológicas, Unidad de Posgrado, Circuito de Posgrados, Ciudad Universitaria, Universidad Nacional Autónoma de México, CP 04510, Mexico City, Mexico.ORCID 0000-0002-3816-1614
Marco V JoséTheoretical Biology Group, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, CP 04510, Mexico City, Mexico.ORCID 0000-0001-8497-6681

Funding

Consejo Nacional de Ciencia y Tecnología (CONACYT) 775924Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México PAPIIT-IN224015Programa de Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México (UNAM)
6 · The paper itself

Abstract

There is an important urgency to detect cancer at early stages to treat it, to improve the patients' lifespans, and even to cure it. In this work, we determined the entropic contributions of genes in cancer networks. We detected sudden changes in entropy values in melanoma, hepatocellular carcinoma, pancreatic cancer, and squamous lung cell carcinoma associated to transitions from healthy controls to cancer. We also identified the most relevant genes involved in carcinogenic process of the four types of cancer with the help of entropic changes in local networks. Their corresponding proteins could be used as potential targets for treatments and as biomarkers of cancer.

Indexed as

average network entropybiomarkerscancerearly warninggene expressionlocal networksmultivariate entropyprotein-protein networks

Identifiers

PMID33265245
PMCPMC7844632

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.