Evidence map›Paper›PMID 33265160›Full record

ArticleEntropy (Basel, Switzerland)2018

Characterizing Normal and Pathological Gait through Permutation Entropy.

Massimiliano Zanin, David Gómez-Andrés, Irene Pulido-Valdeolivas, Juan Andrés Martín-Gonzalo, Javier López-López, Samuel Ignacio Pascual-Pascual, Estrella Rausell

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Gait analysis under the lens of statistical physics.Computational and structural biotechnology journal · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Massimiliano ZaninCenter for Biomedical Technology, Universidad Politécnica de Madrid, Pozuelo de Alarcón, 28223 Madrid, Spain.ORCID 0000-0002-5839-0393
David Gómez-AndrésMOVUAM-TRADESMA laboratory, Department of Anatomy, Histology and Neuroscience, Universidad Autónoma de Madrid, IdiPaz, 28029 Madrid, Spain.ORCID 0000-0001-5654-7791
Irene Pulido-ValdeolivasMOVUAM-TRADESMA laboratory, Department of Anatomy, Histology and Neuroscience, Universidad Autónoma de Madrid, IdiPaz, 28029 Madrid, Spain.ORCID 0000-0003-0188-2458
Juan Andrés Martín-GonzaloMOVUAM-TRADESMA laboratory, Department of Anatomy, Histology and Neuroscience, Universidad Autónoma de Madrid, IdiPaz, 28029 Madrid, Spain.
Javier López-LópezMOVUAM-TRADESMA laboratory, Department of Anatomy, Histology and Neuroscience, Universidad Autónoma de Madrid, IdiPaz, 28029 Madrid, Spain.
Samuel Ignacio Pascual-PascualMOVUAM-TRADESMA laboratory, Department of Anatomy, Histology and Neuroscience, Universidad Autónoma de Madrid, IdiPaz, 28029 Madrid, Spain.
Estrella RausellMOVUAM-TRADESMA laboratory, Department of Anatomy, Histology and Neuroscience, Universidad Autónoma de Madrid, IdiPaz, 28029 Madrid, Spain.ORCID 0000-0002-1129-7116

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral palsy is a physical impairment stemming from a brain lesion at perinatal time, most of the time resulting in gait abnormalities: the first cause of severe disability in childhood. Gait study, and instrumental gait analysis in particular, has been receiving increasing attention in the last few years, for being the complex result of the interactions between different brain motor areas and thus a proxy in the understanding of the underlying neural dynamics. Yet, and in spite of its importance, little is still known about how the brain adapts to cerebral palsy and to its impaired gait and, consequently, about the best strategies for mitigating the disability. In this contribution, we present the hitherto first analysis of joint kinematics data using permutation entropy, comparing cerebral palsy children with a set of matched control subjects. We find a significant increase in the permutation entropy for the former group, thus indicating a more complex and erratic neural control of joints and a non-trivial relationship between the permutation entropy and the gait speed. We further show how this information theory measure can be used to train a data mining model able to forecast the child's condition. We finally discuss the relevance of these results in clinical applications and specifically in the design of personalized medicine interventions.

Indexed as

cerebral palsyinstrumental gait analysispermutation entropy

Identifiers

PMID33265160
PMCPMC7512275

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.