ArticleThe Journal of clinical psychiatry2020
Sexual Orientation, Adverse Childhood Experiences, and Comorbid DSM-5 Substance Use and Mental Health Disorders.
Article in The Journal of clinical psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Prevalence and associated factors of post-traumatic stress disorders among LGBTQI+ adults: a systematic literature review.BMC public health · 2025Pooled it
- Alcohol and cannabis use and Co-use among U.S. sexual minority young adults: Findings from the 2019-2021 monitoring the future longitudinal panel data.Addictive behaviors reports · 2026Article
- Parental death and parental substance use problems during childhood and the risk of DSM-5 substance use, suicidality and mental health disorders.Social psychiatry and psychiatric epidemiology · 2026Article
- Brief transdiagnostic cognitive behavioral therapy and expressive writing for hazardous drinking and posttraumatic stress symptoms among sexual and gender minority adults: Pilot trial protocol.Contemporary clinical trials communications · 2026Article
- Sexual minority adults exhibit greater inflammation than heterosexual adults in the context of depressive symptoms and anxiety: Pathways to health disparities.Brain, behavior, and immunity · 2026Article
- Alcohol Use, Cannabis Use, and Discrimination by Sexual Orientation and Gender Identity Within theLGBT health · 2026Article
- Editorial: Assessment and management of addictive disorders in sexual and racial minorities.Frontiers in psychiatry · 2026Article
- The transgenerational cycle of adverse childhood experiences: transmission and familial factors for intervention - first results of an 18-year German longitudinal study.European journal of psychotraumatology · 2025Article
- Examining bidirectional associations between cannabis use and internalizing symptoms among high-risk emerging adults: A prospective cohort study.Psychological medicine · 2025Article
- Socioenvironmental and mental health determinants of alcohol use among Black sexually minoritized men and transgender women: Findings from the N2 cohort study.Journal of gay & lesbian mental health · 2025Article
- Adverse Childhood Experiences and Health Outcomes Among Transition-Age Autistic Youth.Journal of autism and developmental disorders · 2025Article
- Associations of sexual orientation and state-level antidiscrimination policy protections with alcohol, tobacco, and mental health outcomes in a U.S. sample of adolescents and adults.Social science & medicine (1982) · 2025Article
- Adolescents' Adverse Childhood Experiences, Poor Mental Health, and Substance Use During the COVID-19 Pandemic.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Co-Vaping of Nicotine and Cannabis by Sexual Identity Among US Adults: Results From the 2022 National Survey on Drug Use and Health.American journal of preventive medicine · 2024Article
- Proposed Physiological Mechanisms Underlying the Association between Adverse Childhood Experiences and Mental Health Conditions: A Narrative Review.Children (Basel, Switzerland) · 2024Review
- Associations of sexual identity change and identity-attraction discordance with symptomatic alcohol and other drug use.Social psychiatry and psychiatric epidemiology · 2024Article
- A national longitudinal study of sexual orientation discordance, sexual identity fluidity, and alcohol and other drug use disorder symptoms.The American journal of drug and alcohol abuse · 2024Article
- Adverse Childhood Experiences and Health Outcomes Among Sexual and Gender Minorities: A Systematic Review.Journal of child & adolescent trauma · 2024Article
- Childhood sexual abuse, adult sexual assault, revictimization, and coping among sexual minority women.Child abuse & neglect · 2024Article
- Childhood Adversity and Adolescent Smartphone Use Across Sexual Orientation and Gender Expression.JAMA network open · 2024Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo assess the relationships between adverse childhood experiences (ACEs) and comorbid Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) substance use and mental health disorders across 5 sexual orientation subgroups: lesbian/gay, bisexual, unsure, discordant heterosexual (ie, heterosexual-identified with same-sex attraction or behavior), and concordant heterosexual.
methodsData were from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions-III, a cross-sectional, nationally representative survey of non-institutionalized US adults. Data were collected in households via structured diagnostic face-to-face interviews; the overall response rate was 60.1%. The sample included 36,309 US adults aged 18 years and older.
resultsSexual minorities (gay, lesbian, bisexual), especially bisexual women, reported the highest prevalence of ACEs and comorbid substance use and mental health disorders. Approximately 43.8% of bisexual women reported 4 or more ACEs, and 38.0% of bisexual women reported comorbid substance use and mental health disorders. Multivariable regression analyses indicated a curvilinear relationship between ACEs and comorbid substance use and mental health disorders, and sexual minorities consistently had a higher ACE mean than concordant heterosexual respondents. The majority of sexual minorities with high levels of ACEs had comorbid substance use and mental health disorders.
conclusionsSexual minorities are exposed to more ACEs than their heterosexual counterparts in the US. We found evidence that US sexual minorities are at higher risk of comorbid substance use and mental health disorders. These findings reinforce the importance of identifying exposure to ACEs and developing trauma-informed interventions to treat comorbidities in those exposed to multiple ACEs, especially sexual minorities..
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.