ArticleeLife2020
RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Directed evolution of Clec12a-binding peptides using mammalian-expressed recombinant protein.Biochemistry and biophysics reports · 2026Article
- Pattern recognition receptors: function, regulation and therapeutic potential.Signal transduction and targeted therapy · 2025Review
- Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials.NPJ vaccines · 2025Review
- Single-shot dendritic cell targeting SARS-CoV-2 vaccine candidate induces broad, durable and protective systemic and mucosal immunity in mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2024Article
- A Simple and Rapid Protocol for the Isolation of Murine Bone Marrow Suitable for the Differentiation of Dendritic Cells.Methods and protocols · 2024Article
- Role of Ubiquitin Signaling in Modulating Dendritic Cell Function.Advances in experimental medicine and biology · 2024Review
- Plasma Proteomics Unveil Novel Immune Signatures and Biomarkers upon SARS-CoV-2 Infection.International journal of molecular sciences · 2023Article
- Mapping the tumor microenvironment in clear cell renal carcinoma by single-cell transcriptome analysis.Frontiers in genetics · 2023Article
- Single cell RNA sequencing reveals distinct clusters of Irf8-expressing pulmonary conventional dendritic cells.Frontiers in immunology · 2023Article
- CLEC-1 is a death sensor that limits antigen cross-presentation by dendritic cells and represents a target for cancer immunotherapy.Science advances · 2022Article
- Vaccine adjuvants to engage the cross-presentation pathway.Frontiers in immunology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 5 institutions in 2 countries.
Kirsteen M Tullett *Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.ORCID 0000-0002-2389-9819
Peck Szee Tan *Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.ORCID 0000-0002-8808-7125
Hae-Young ParkInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
Ralf B SchittenhelmMonash Proteomics and Metabolomics Facility, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
Nicole MichaelInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
Rong LiCentre for Biomedical Research, Burnet Institute, Melbourne, Australia.
Antonia N PolicheniThe Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Emily GruberInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
Cheng HuangMonash Proteomics and Metabolomics Facility, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
Alex J FulcherMonash Micro Imaging Facility, Monash University, Clayton, Australia.
Jillian C DanneRamaciotti Centre for Cryo-Electron Microscopy, Monash University, Clayton, Australia.
Peter E CzabotarThe Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Linda M WakimDepartment of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia.
Justine D MinternDepartment of Biochemistry and Molecular Biology at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, Australia.
Georg RammInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
Kristen J RadfordMater Research Institute - University of Queensland, Translational Research Institute, Brisbane, Australia.
Irina CaminschiInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
Meredith O'KeeffeInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
Jose A VilladangosDepartment of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia.
Mark D WrightDepartment of Immunology, Monash University, Melbourne, Australia.
Marnie E BlewittThe Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0002-2984-1474
William R HeathDepartment of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia.
Ken ShortmanThe Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Anthony W PurcellInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
Nicos A NicolaThe Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Jian-Guo ZhangThe Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Mireille H LahoudInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.ORCID 0000-0001-8472-6201
The University of Melbourne · AUDiscovery Institute · USMonash University · AUBurnet Institute · AUTranslational Research Institute · AU
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction of effective CD8
Indexed as
AnimalsAntigensCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCHO CellsCricetinaeCricetulusDendritic CellsGene Expression RegulationLectins, C-TypeMiceMice, Inbred C57BLMice, KnockoutProtein BindingReceptors, ImmunologicUbiquitin-Protein LigasesAntigensClec9a protein, mouseLectins, C-TypeReceptors, ImmunologicRnf41 protein, mouseUbiquitin-Protein Ligasesantigen presentationDAMP recognitiondendritic cellsE3 ubiquitin ligaseimmunologyinflammationmouseubiquitination
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.