Evidence map›Paper›PMID 33263889›Full record

ArticleResults and problems in cell differentiation2020

The Macrophages and Intestinal Symbiosis.

Malgorzata Kloc, Ahmed Uosef, Mahmoud Elshawwaf, Ahmed Adel Abbas Abdelshafy, Kamal Mamdoh Kamal Elsaid, Jacek Z Kubiak, Rafik Mark Ghobrial

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Article in Results and problems in cell differentiation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Malgorzata KlocThe Houston Methodist Research Institute, Houston, TX, USA. mkloc@houstonmethodist.org.
Ahmed UosefThe Houston Methodist Research Institute, Houston, TX, USA.
Mahmoud ElshawwafThe Houston Methodist Research Institute, Houston, TX, USA.
Ahmed Adel Abbas AbdelshafyThe Houston Methodist Research Institute, Houston, TX, USA.
Kamal Mamdoh Kamal ElsaidThe Houston Methodist Research Institute, Houston, TX, USA.
Jacek Z KubiakDepartment of Regenerative Medicine and Cell Biology, Military Institute of Hygiene and Epidemiology (WIHE), Warszawa, Poland.
Rafik Mark GhobrialThe Houston Methodist Research Institute, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human intestinal tract is inhabited by trillions of microorganisms and houses the largest pool of macrophages in the human body. Being a part of the innate immune system, the macrophages, the professional phagocytes, vigorously respond to the microbial and dietary antigens present in the intestine. Because such a robust immune response poses the danger to the survival of the non-harmful and beneficial gut microbiota, the macrophages developed mechanisms of recognition and hyposensitivity toward the non-harmful/beneficial inhabitants of the gut. We will discuss the evolution and identity of some of these mechanisms in the following chapter.

Indexed as

Gastrointestinal MicrobiomeHost Microbial InteractionsSymbiosisHumansImmunityMacrophages

Identifiers

PMID33263889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.