Evidence map›Paper›PMID 33263821›Full record

ReviewCurrent oncology reports2020

Cancer Risk in the Heart Failure Population: Epidemiology, Mechanisms, and Clinical Implications.

Alessandra Cuomo, Flora Pirozzi, Umberto Attanasio, Riccardo Franco, Francesco Elia, Eliana De Rosa, Michele Russo, Alessandra Ghigo, Pietro Ameri, Carlo Gabriele Tocchetti and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in Current oncology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  4. Cardio-Oncology Challenges in Elderly Patients.Journal of clinical medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Alessandra CuomoDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Flora PirozziDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Umberto AttanasioDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Riccardo FrancoDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Francesco EliaDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Eliana De RosaDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Michele RussoDepartment of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.
Alessandra GhigoDepartment of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.
Pietro AmeriCardiovascular Disease Unit, IRCCS Italian Cardiovascular Network, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Carlo Gabriele TocchettiDepartment of Translational Medical Sciences, Federico II University, Naples, Italy. carlogabriele.tocchetti@unina.it.ORCID 0000-0001-5983-688X
Valentina MercurioDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Federico II University Hospital · ITUniversity of Turin · ITOspedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAlong with population aging, the incidence of both heart failure (HF) and cancer is increasing. However, little is known about new-onset cancer in HF patients. This review aims at showing recent discoveries concerning this subset of patients. RECENT

findingsNot only cancer and HF share similar risk factors but also HF itself can stimulate cancer development. Some cytokines produced by the failing heart induce mild inflammation promoting carcinogenesis, as it has been recently suggested by an experimental model of HF in mice. The incidence of new-onset cancer is higher in HF patients compared to the general population, and it significantly worsens their prognosis. Moreover, the management of HF patients developing new-onset cancer is challenging, especially due to the limited therapeutic options for patients affected by both cancer and HF and the higher risk of cardiotoxicity from anticancer drugs.

Indexed as

Antineoplastic AgentsCardiotoxicityHeart FailureHumansIncidenceNeoplasmsRisk FactorsAntineoplastic AgentsAgingCancerCardio-oncologyHeart failurePathophysiologyRisk factors

Identifiers

PMID33263821
PMCPMC7716920
OpenAlexW3106714712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.