ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2020
Asymptomatic Leishmania infection in blood donors from a major blood bank in Northeastern Brazil: a cross-sectional study.
Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Patterns and drivers of the distribution of Leishmania infection in humans using environmental and socioeconomic factors: a modeling study in mainland Portugal.Parasites & vectors · 2026Article
- Assessment of Leishmania exposure in blood donors from a non-endemic urban area: A study in São Paulo.Vox sanguinis · 2026Article
- Autochthonous Leishmaniasis in the United States of America.Microorganisms · 2025Review
- A one-step multiplex qPCR assay for simultaneous identification and quantification of Leishmania martiniquensis and Leishmania orientalis/Leishmania chancei and detection and quantification of trypanosomatids in clinical samples.Parasite (Paris, France) · 2025Article
- Asymptomatic Leishmania Infection among Blood Donors in a Southern Province of Thailand.The American journal of tropical medicine and hygiene · 2024Article
- Prevalence of Leishmaniasis among Blood Donors: A Systematic Review and Meta-Analysis.Diseases (Basel, Switzerland) · 2024Review
- Chagas Disease and Leishmaniasis, Sympatric Zoonoses Present in Human from Rural Communities of Venezuela.Acta parasitologica · 2024Article
- Erythrocyte sedimentation rate in heartworm naturally infected dogs "with or without"Frontiers in veterinary science · 2024Article
- Prevalence of asymptomatic Leishmania infection and knowledge, perceptions, and practices in blood donors in mainland Portugal.Parasites & vectors · 2023Article
- Article
- Identification of asymptomatic Leishmania infections: a scoping review.Parasites & vectors · 2022Article
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study has estimated the risk of Leishmania transmission via blood transfusion in one of the largest blood banks in Northeastern Brazil, where visceral leishmaniasis is endemic. Five hundred blood samples from donors were tested for circulating Leishmania spp. DNA by real-time PCR. Positive samples were tested by a species-specific conventional PCR targeting Leishmania infantum . Overall, 6.2% (95% CI: 4.1-8.3%) of the samples carried Leishmania DNA and in one sample the species was confirmed as L. infantum . No statistically significant differences were found in relation to gender, sex, education level, incomeas well as the place of residence between positive and negative blood donors. Our results confirm the presence of asymptomatic Leishmania carriers among blood donors in a large blood bank in Northeastern Brazil. Considering the studied population, we estimate that for every 1,000 blood donors screened, 41 to 83 will be positive for Leishmania DNA. This finding reinforces the urgent need for elaborating specific Blood bank guidelines to allow the early detection of asymptomatic Leishmania carriers among blood donors before their blood products are transfused to uninfected individuals.
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