Evidence map›Paper›PMID 33263419›Full record

ReviewAJR. American journal of roentgenology2021

Secretin-Enhanced MRCP: How and Why-

Jordan Swensson, Atif Zaheer, Darwin Conwell, Kumar Sandrasegaran, Riccardo Manfredi, Temel Tirkes

Open access · greenAbstract readReview
In one paragraph

Review in AJR. American journal of roentgenology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jordan SwenssonDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N University Blvd, Rm 0663, Indianapolis, IN 46202.
Atif ZaheerDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N University Blvd, Rm 0663, Indianapolis, IN 46202.
Darwin ConwellDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH.
Kumar SandrasegaranDepartment of Diagnostic Radiology, Mayo Clinic, Scottsdale, AZ.
Riccardo ManfrediDepartment of Diagnostic Imaging, Oncological Radiotherapy, and Hematology, Diagnostic Imaging Area, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Temel TirkesDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N University Blvd, Rm 0663, Indianapolis, IN 46202.
Johns Hopkins University · USMayo Clinic in Arizona · USThe Ohio State University Wexner Medical Center · US

Funding

Indiana University (IU) Clinical Center for Chronic Pancreatitis Clinical Research NetworkU01DK108323 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Jeffrey James Easler, Evan L Fogel · 2015 to 2026
$6.5M
Indiana University clinical Center for acute pancreatitis and diabetes clinical research networkU01DK127382 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina, Evan L Fogel · 2020 to 2026
$2.4M
Magnetic resonance Imaging as a Non-Invasive Method for Assessment of Pancreatic fibrosis (MINIMAP): a pilot studyR01DK116963 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI FOGEL, EVAN L, TIRKES, TEMEL · 2018 to 2020
$2.0M
NIDDK NIH HHS R01 DK116963NIDDK NIH HHS U01 DK108323NIDDK NIH HHS U01 DK127382
6 · The paper itself

Abstract

Secretin-enhanced MRCP (S-MRCP) has advantages over standard MRCP for imaging of the pancreaticobiliary tree. Through the use of secretin to induce fluid production from the pancreas and leveraging of fluid-sensitive MRCP sequences, S-MRCP facilitates visualization of ductal anatomy, and the findings provide insight into pancreatic function, allowing radiologists to provide additional insight into a range of pancreatic conditions. This narrative review provides detailed information on the practical implementation of S-MRCP, including patient preparation, logistics of secretin administration, and dynamic secretin-enhanced MRCP acquisition. Also discussed are radiologists' interpretation and reporting of S-MRCP examinations, including assessments of dynamic compliance of the main pancreatic duct and of duodenal fluid volume. Established indications for S-MRCP include pancreas divisum, anomalous pancreaticobiliary junction, Santorinicele, Wirsungocele, chronic pancreatitis, main pancreatic duct stenosis, and assessment of complex postoperative anatomy. Equivocal or controversial indications are also described along with an approach to such indications. These indications include acute and recurrent acute pancreatitis, pancreatic exocrine function, sphincter of Oddi dysfunction, and pancreatic neoplasms.

Indexed as

Cholangiopancreatography, Magnetic ResonanceHumansImage EnhancementPancreasPancreatic DiseasesPeriodicals as TopicSecretinSecretinMRCPMRIpancreassecretin

Identifiers

PMID33263419
PMCPMC8068672
OpenAlexW3108555363

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.