ArticleEuropean radiology2021
3D Dixon water-fat LGE imaging with image navigator and compressed sensing in cardiac MRI.
Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 29 citations in OpenAlex.
- Quantitative detection of left atrial fibrosis in patients with atrial fibrillation: a comparative study of two 3D whole-heart late gadolinium enhancement sequences.The international journal of cardiovascular imaging · 2026Article
- AI-powered SPOT imaging for enhanced myocardial scar detection and quantification.Nature communications · 2025Article
- Improving tissue contrast visualization in two-point Dixon MRI using dark-fat processing: application in clinical knee imaging.Skeletal radiology · 2025Article
- Highly accelerated, Dixon-based non-contrast MR angiography versus high-pitch CT angiography.La Radiologia medica · 2024Article
- Evaluating prostate cancer bone metastasis using accelerated whole-body isotropic 3D T1-weighted Dixon MRI with compressed SENSE: a feasibility study.European radiology · 2023Article
- Compressed SENSE accelerated 3D single-breath-hold late gadolinium enhancement cardiovascular magnetic resonance with isotropic resolution: clinical evaluation.Frontiers in cardiovascular medicine · 2023Article
- Myocardial scar detection in free-breathing Dixon-based fat- and water-separated 3D inversion recovery late-gadolinium enhancement whole heart MRI.The international journal of cardiovascular imaging · 2023Article
- Simultaneous Assessment of Left Atrial Fibrosis and Epicardial Adipose Tissue Using 3D Late Gadolinium Enhanced Dixon MRI.Journal of magnetic resonance imaging : JMRI · 2022Article
- Isotropic 3D compressed sensing (CS) based sequence is comparable to 2D-LGE in left ventricular scar quantification in different disease entities.The international journal of cardiovascular imaging · 2022Article
- Whole-Heart High-Resolution Late Gadolinium Enhancement: Techniques and Clinical Applications.Journal of magnetic resonance imaging : JMRI · 2022Review
- Recent advances in PET-MRI for cardiac sarcoidosis.Frontiers in nuclear medicine · 2022Review
- A Fast CS-Based Reconstruction Model with Total Variation Constraint for MRI Enhancement in K-Space Domain.Computational intelligence and neuroscience · 2022Article
- Evaluation of accelerated motion-compensated 3d water/fat late gadolinium enhanced MR for atrial wall imaging.Magma (New York, N.Y.) · 2021Article
- Single-Breath-Hold MRI-SPACE Cholangiopancreatography with Compressed Sensing versus Conventional Respiratory-Triggered MRI-SPACE Cholangiopancreatography at 3Tesla: Comparison of Image Quality and Diagnostic Confidence.Diagnostics (Basel, Switzerland) · 2021Article
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Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
Abstract
objectivesTo evaluate an image-navigated isotropic high-resolution 3D late gadolinium enhancement (LGE) prototype sequence with compressed sensing and Dixon water-fat separation in a clinical routine setting. MATERIAL AND
methodsForty consecutive patients scheduled for cardiac MRI were enrolled prospectively and examined with 1.5 T MRI. Overall subjective image quality, LGE pattern and extent, diagnostic confidence for detection of LGE, and scan time were evaluated and compared to standard 2D LGE imaging. Robustness of Dixon fat suppression was evaluated for 3D Dixon LGE imaging. For statistical analysis, the non-parametric Wilcoxon rank sum test was performed.
resultsLGE was rated as ischemic in 9 patients and non-ischemic in 11 patients while it was absent in 20 patients. Image quality and diagnostic confidence were comparable between both techniques (p = 0.67 and p = 0.66, respectively). LGE extent with respect to segmental or transmural myocardial enhancement was identical between 2D and 3D (water-only and in-phase). LGE size was comparable (3D 8.4 ± 7.2 g, 2D 8.7 ± 7.3 g, p = 0.19). Good or excellent fat suppression was achieved in 93% of the 3D LGE datasets. In 6 patients with pericarditis, the 3D sequence with Dixon fat suppression allowed for a better detection of pericardial LGE. Scan duration was significantly longer for 3D imaging (2D median 9:32 min vs. 3D median 10:46 min, p = 0.001).
conclusionThe 3D LGE sequence provides comparable LGE detection compared to 2D imaging and seems to be superior in evaluating the extent of pericardial involvement in patients suspected with pericarditis due to the robust Dixon fat suppression. KEY POINTS: • Three-dimensional LGE imaging provides high-resolution detection of myocardial scarring. • Robust Dixon water-fat separation aids in the assessment of pericardial disease. • The 2D image navigator technique enables 100% respiratory scan efficacy and permits predictable scan times.
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