Evidence map›Paper›PMID 33262952›Full record

ArticleFrontiers in oncology2020

Circular RNA circGSK3B Promotes Cell Proliferation, Migration, and Invasion by Sponging miR-1265 and Regulating

Kai Li, Jiacheng Cao, Zitong Zhang, Keyan Chen, Tieliang Ma, Wenjie Yang, Shikun Yang, Jianhua Rao, Kai Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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  5. Glutamine metabolic reprogramming in hepatocellular carcinoma.Frontiers in molecular biosciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Kai LiDepartment of General Surgery, The Affiliated Yixing Hospital of Jiangsu University, Yixing, China.
Jiacheng CaoDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zitong ZhangDepartment of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Keyan ChenDepartment of General Surgery, The Affiliated Yixing Hospital of Jiangsu University, Yixing, China.
Tieliang MaCentral Laboratory, The Affiliated Yixing Hospital of Jiangsu University, Yixing, China.
Wenjie YangHepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Key Laboratory on Living Donor Liver Transplantation of National Health and Family Planning Commission of China, Nanjing, China.
Shikun YangHepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Key Laboratory on Living Donor Liver Transplantation of National Health and Family Planning Commission of China, Nanjing, China.
Jianhua RaoHepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Key Laboratory on Living Donor Liver Transplantation of National Health and Family Planning Commission of China, Nanjing, China.
Kai ZhangDepartment of General Surgery, The Affiliated Yixing Hospital of Jiangsu University, Yixing, China.
Nanjing Medical University · CNJiangsu University · CNYixing People's Hospital · CNJiangsu Province Hospital · CNNational Health and Family Planning Commission · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) have important regulatory roles in the development of various cancers. However, the biological functions and potential molecular mechanisms of circRNAs in hepatocellular carcinoma (HCC) are still unclear. In this study, we investigated the role of a new circRNA-circGSK3B (hsa_circ_0003763) and its molecular mechanism in HCC. We found that circGSK3B was highly expressed in HCC tissues and HCC cell lines. Additionally, the expression level of circGSK3B significantly correlated with HCC tumor size and vascular invasion. Functionally, we confirmed that circGSK3B can promote the proliferation, migration, and invasion of HCC cells

Indexed as

CAB39circGSK3Bglutaminolysishepatocellular carcinomamiR-1265QKI

Identifiers

PMID33262952
PMCPMC7688052
OpenAlexW3102252217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.