Evidence map›Paper›PMID 33262932›Full record

ArticleCase reports in women's health2021

Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report.

Jennifer Jacobson, Kathleen Antony, Michael Beninati, William Alward, Kara K Hoppe

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in women's health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Pregnancy and COVID-19.Journal of clinical medicine · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. A review of remdesivir for COVID-19 in pregnancy and lactation.The Journal of antimicrobial chemotherapy · 2021
    Review
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jennifer JacobsonDepartment of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Kathleen AntonyDepartment of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Michael BeninatiDepartment of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
William AlwardDepartment of Pulmonology and Critical Care, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Kara K HoppeDepartment of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
University of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe infection with COVID-19 virus in pregnancy offers unique management challenges for the obstetrician and critical care specialist. We report the case of a woman at 26 weeks of gestation with acute respiratory distress syndrome secondary to COVID-19 infection treated with dexamethasone, remdesivir, convalescent plasma and mechanical ventilation. Cesarean delivery was performed at 29 weeks due to worsening maternal status. This case offers insight into the assessment and successful use of treatment strategies, including dexamethasone, remdesivir, convalescent plasma, early prone positioning, conservative fluid management, permissive hypoxia and low tidal volume parameters with ventilator support for pregnancies affected by severe COVID-19 infection.

Indexed as

Acute respiratory distress syndrome (ARDS)COVID-19DexamethasonePregnancyProneRespiratory failure

Identifiers

PMID33262932
PMCPMC7687655
OpenAlexW3107929821

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.