Evidence map›Paper›PMID 33262758›Full record

ReviewFrontiers in immunology2020

Inflammaging in Endemic Areas for Infectious Diseases.

Marina Andrade Batista, Fernanda Calvo-Fortes, Gabriela Silveira-Nunes, Giovanna Caliman Camatta, Elaine Speziali, Silvia Turroni, Andrea Teixeira-Carvalho, Olindo A Martins-Filho, Nicola Neretti, Tatiani Uceli Maioli and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 36 citations in OpenAlex.

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  10. IL-17 as a putative hallmark of intense arthralgia and age-related serum immune mediator networks during acute chikungunya fever.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Marina Andrade BatistaPrograma de Pós Graduação em Nutrição e Saúde, Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Fernanda Calvo-FortesPrograma de Pós Graduação em Nutrição e Saúde, Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Gabriela Silveira-NunesDepartamento de Medicina, Universidade Federal de Juiz de Fora, Governador Valadares, Brazil.
Giovanna Caliman CamattaPrograma de Pós Graduação em Nutrição e Saúde, Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Elaine SpezialiInstituto Rene Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
Silvia TurroniUnit of Microbial Ecology of Health, Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Andrea Teixeira-CarvalhoInstituto Rene Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
Olindo A Martins-FilhoInstituto Rene Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
Nicola NerettiDepartament of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, United States.
Tatiani Uceli MaioliPrograma de Pós Graduação em Nutrição e Saúde, Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Rodrigo Ribeiro SantosDepartamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Patrizia BrigidiUnit of Microbial Ecology of Health, Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Claudio FranceschiCenter for Biophysics, Bioinformatics, Biocomplexity, University of Bologna, Bologna, Italy.
Ana Maria Caetano FariaPrograma de Pós Graduação em Nutrição e Saúde, Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Universidade Federal de Minas Gerais · BRFundação Oswaldo Cruz · BRUniversity of Bologna · ITBrown University · USN. I. Lobachevsky State University of Nizhny Novgorod · RUUniversidade Federal de Juiz de Fora · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunosenescence is marked by a systemic process named inflammaging along with a series of defects in the immunological activity that results in poor responses to infectious agents and to vaccination. Inflammaging, a state of low-grade chronic inflammation, usually leads to chronic inflammatory diseases and frailty in the elderly. However, some elderly escape from frailty and reach advanced age free of the consequences of inflammaging. This process has been called immunological remodeling, and it is the hallmark of healthy aging as described in the studies of centenarians in Italy. The biological markers of healthy aging are still a matter of debate, and the studies on the topic have focused on inflammatory

Indexed as

AgingAnimalsCommunicable DiseasesDiet, WesternEndemic DiseasesFrailtyHealthy AgingHumansImmunosenescenceInflammationItalyMicrobiotaagingchronic infectiondietary componentsgeneticsinflammaginginflammationmicrobiota

Identifiers

PMID33262758
PMCPMC7688519
OpenAlexW3104541273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.