Evidence map›Paper›PMID 33262755›Full record

ArticleFrontiers in immunology2020

Serpinb1a Is Dispensable for the Development and Cytokine Response of Invariant Natural Killer T Cell Subsets.

Nathan G F Leborgne, Adriano Taddeo, Stefan Freigang, Charaf Benarafa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nathan G F LeborgneInstitute of Virology and Immunology, Mittelhäusern, Switzerland.
Adriano TaddeoInstitute of Virology and Immunology, Mittelhäusern, Switzerland.
Stefan FreigangInstitute of Pathology, University of Bern, Bern, Switzerland.
Charaf BenarafaInstitute of Virology and Immunology, Mittelhäusern, Switzerland.
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invariant natural killer T (iNKT) cells are innate-like T lymphocytes. They quickly respond to antigenic stimulation by producing copious amounts of cytokines and chemokines. iNKT precursors differentiate into three subsets iNKT1, iNKT2, and iNKT17 with specific cytokine production signatures. While key transcription factors drive subset differentiation, factors that regulate iNKT subset homeostasis remain incompletely defined. Transcriptomic analyses of thymic iNKT subsets indicate that

Indexed as

AnimalsCell DifferentiationCytokinesDendritic CellsFemaleGalactosylceramidesHomeostasisInflammationLiverLungLymphocyte ActivationMaleMiceMice, Inbred C57BLMice, KnockoutModels, Animalalpha-galactosylceramideCytokinesGalactosylceramidesSerpinb1a protein, mouseSerpinscytokine responseinnate immunityinvariant NKTserpinα-galactosylceramide

Identifiers

PMID33262755
PMCPMC7686238
OpenAlexW3100870547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.