Evidence map›Paper›PMID 33262745›Full record

ArticleFrontiers in microbiology2020

Molecular Characterization of Extended-Spectrum β-Lactamase-Producing

Andres Perez-Lopez, Sathyavathi Sundararaju, Hassan Al-Mana, Kin Ming Tsui, Mohammad Rubayet Hasan, Mohammed Suleiman, Mohammed Janahi, Eman Al Maslamani, Patrick Tang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Systematic review of multidrug-resistantFrontiers in microbiology · 2025
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  6. Emerging carbapenem-resistantMicrobiology spectrum · 2025
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  7. Characterization ofJAC-antimicrobial resistance · 2024
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  9. Genetic characterization of plasmid-mediated fluoroquinolone efflux pump QepA among ESBL-producing Escherichia coli isolates in Mexico.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  10. Article
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  12. Genomic Epidemiology of Carbapenem-ResistantAntimicrobial agents and chemotherapy · 2023
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Multidrug-Resistant High-RiskAntibiotics (Basel, Switzerland) · 2022
    Article
  18. Evaluation ofOman medical journal · 2022
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Andres Perez-LopezDivision of Microbiology, Department of Pathology, Sidra Medicine, Doha, Qatar.
Sathyavathi SundararajuDivision of Microbiology, Department of Pathology, Sidra Medicine, Doha, Qatar.
Hassan Al-ManaDivision of Microbiology, Department of Pathology, Sidra Medicine, Doha, Qatar.
Kin Ming TsuiDivision of Microbiology, Department of Pathology, Sidra Medicine, Doha, Qatar.
Mohammad Rubayet HasanDivision of Microbiology, Department of Pathology, Sidra Medicine, Doha, Qatar.
Mohammed SuleimanDivision of Microbiology, Department of Pathology, Sidra Medicine, Doha, Qatar.
Mohammed JanahiWeill Cornell Medical College in Qatar, Doha, Qatar.
Eman Al MaslamaniWeill Cornell Medical College in Qatar, Doha, Qatar.
Patrick TangDivision of Microbiology, Department of Pathology, Sidra Medicine, Doha, Qatar.
Weill Cornell Medical College in Qatar · QAQatar University · QAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough extended-spectrum β-lactamase (ESBL)-producing Enterobacterales are a public health problem in the Arabian Peninsula, data on the molecular characteristic of their antimicrobial resistance determinants in children is limited.

aimTo determine the molecular characteristics of ESBL-producing

methodsWhole-genome sequencing was performed on ESBL-producing

resultsA total of 327 ESBL producers were sequenced: 254

conclusionOur data show that CTX-M enzymes are largely the most prevalent ESBLs in children in Qatar with a predominance of CTX-M-15. Carbapenem-sparing options to treat ESBL infections are limited, given the frequent coproduction of OXA-1 and TEM-1B enzymes and coresistance to antibiotic classes other than β-lactams.

Indexed as

childrenCTX-M-15E. coliextended-spectrum β-lactamasesfluoroquinolonesK. pneumoniaewhole-genome sequencing

Identifiers

PMID33262745
PMCPMC7686840
OpenAlexW3098086588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.